7
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      The pharmacokinetics and effects of meloxicam, gabapentin, and flunixin in postweaning dairy calves following dehorning with local anesthesia

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Related collections

          Most cited references39

          • Record: found
          • Abstract: found
          • Article: not found

          Reducing pain after dehorning in dairy calves.

          We investigated behavioral responses after dehorning and a sham procedure in 20 Holstein calves aged 4 to 8 wk. Calves either received a nonsteroidal antiinflammatory drug (ketoprofen) before dehorning as well as 2 and 7 h after the procedure or were assigned to a control group. All calves received a sedative (xylazine) and local anaesthetic (lidocaine) before dehorning, and responses were scored over 24 h after the procedure. After hot-iron dehorning, calves treated with ketoprofen also demonstrated little head shaking or ear flicking, but control animals demonstrated higher frequencies of these behaviors; both responses peaked 6 h after dehorning. Differences between the treatment groups remained statistically significant until 12 h (head shaking) and 24 h (ear flicking) after dehorning. A low frequency of head rubbing was observed in both treatment groups, but control calves were more frequently observed engaged in this behavior. There was no statistically significant effect of treatment on any of the other behavioral measures. Calves treated with ketoprofen also tended to gain more weight (1.2+/-0.4 kg) during the 24 h after dehorning than did control calves (0.2+/-0.4 kg). There was no effect of treatment on any of the response variables when calves were sham dehorned. These results indicate that ketoprofen mitigates pain after hot-iron dehorning in young dairy calves.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Behavioural and physiological responses of calves to dehorning by heat cauterization with or without local anaesthesia

              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Plasma concentrations of substance P and cortisol in beef calves after castration or simulated castration.

              To evaluate plasma concentrations of substance P (SP) and cortisol in calves after castration or simulated castration. 10 Angus-crossbred calves. Calves were acclimated for 5 days, assigned to a block on the basis of scrotal circumference, and randomly assigned to a castrated or simulated-castrated (control) group. Blood samples were collected twice before, at the time of (0 hours), and at several times points after castration or simulated castration. Vocalization and attitude scores were determined at time of castration or simulated castration. Plasma concentrations of SP and cortisol were determined by use of competitive and chemiluminescent enzyme immunoassays, respectively. Data were analyzed by use of repeated-measures analysis with a mixed model. Mean +/- SEM cortisol concentration in castrated calves (78.88+/-10.07 nmol/L) was similar to that in uncastrated control calves (73.01+/-10.07 nmol/L). However, mean SP concentration in castrated calves (506.43+/-38.11 pg/mL) was significantly higher than the concentration in control calves (386.42+/-40.09 pg/mL). Mean cortisol concentration in calves with vocalization scores of 0 was not significantly different from the concentration in calves with vocalization scores of 3. However, calves with vocalization scores of 3 had significantly higher SP concentrations, compared with SP concentrations for calves with vocalization scores of 0. Similar cortisol concentrations were measured in castrated and control calves. A significant increase in plasma concentrations of SP after castration suggested a likely association with nociception. These results may affect assessment of animal well-being in livestock production systems.
                Bookmark

                Author and article information

                Journal
                Journal of Veterinary Pharmacology and Therapeutics
                J. Vet. Pharmacol. Ther.
                Wiley
                01407783
                December 2013
                December 08 2013
                : 36
                : 6
                : 550-561
                Article
                10.1111/jvp.12042
                23473342
                c0cc3523-9e1d-48a0-ae7f-cb996e117074
                © 2013

                http://doi.wiley.com/10.1002/tdm_license_1.1

                History

                Comments

                Comment on this article