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      Conducta médica posnatal ante la dilatación del tracto urinario superior fetal Translated title: Postnatal medical behavior in face a dilatation of fetal high urinary tract

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          Abstract

          El seguimiento sistemático del embarazo normal mediante el estudio ultrasonográfico materno-fetal ha demostrado que por cada 500 embarazos debemos esperar una anomalía importante del tracto urinario. La anomalía detectada con mayor frecuencia es la dilatación del tracto urinario superior, que si bien la mayoría de las veces no se traduce en una alteración importante, obliga a su estudio posnatal para poder valorar su significación. Una dilatación del tracto urinario superior puede ser la traducción de una hidronefrosis obstructiva por estenosis ureteropiélica, una hidronefrosis no obstructiva, un reflujo vesicoureteral o una pielectasia, y menos frecuentemente, puede ser la imagen de un doble sistema excretor con el superior obstruido, un megauréter obstructivo o no obstructivo, o una valva de uretra posterior en el sexo masculino. En esta revisión se presentan los criterios diagnósticos y el tratamiento clínico de las hidronefrosis y pielectasias, así como el estudio de los casos en que se sospecha reflujo vesicoureteral, y se relatan las anomalías encontradas en 318 niños en que el ultrasonido materno-fetal detectó alguna alteración del tracto urinario. Aunque no tan frecuente como las pielectasias y las hidronefrosis no obstructivas, las estenosis pieloureterales que producen obstrucción, pueden traer serias consecuencias sobre la función renal, que obligan a tomar decisiones médicas, y, en ocasiones, quirúrgicas, para mejorar la calidad de vida de estos niños.

          Translated abstract

          The systematic follow-up of the normal pregnancy by means of a mother-fetus ultrasonography study has demonstrated that for each 500 pregnancies, we must to expect a significant anomaly of urinary tract. The more frequent anomaly detected is the high urinary tract dilatation, which if not always it is a significant alteration, leads to a postnatal study to assess its significance. A high urinary tract dilatation may to give rise to an obstructive hydronephrosis due to ureteropyelitis anastomosis; a non-obstructive hydronephrosis, a vesicoureteral reflux or a pyelectasia and less frequently may be an image of double excretory system with the superior one obstructed, an obstructive or not megaureter, or a valve or the posterior urethra in male sex. In present review are showed the diagnostic criteria and the clinical treatment of the hydronephrosis and the pyelectasia, as well as the study cases with suspicion of vesicoureteral reflux mentioning the anomalies founded in 318 children in whom the mother-fetus ultrasound detected some alteration of the urinary tract. Although not so frequent as the non-obstructive pyelectasia and the hydronephrosis, the pyeloureteral stenosis producing obstruction, may give rise to serious consequences on the renal function leading to make a medical decision, and occasionally, of surgical type to improve the quality of life of these children.

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          Most cited references86

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          Antenatal hydronephrosis as a predictor of postnatal outcome: a meta-analysis.

          Antenatal hydronephrosis is diagnosed in 1% to 5% of all pregnancies; however, the antenatal and postnatal management of hydronephrosis varies widely. No previous studies define the risk of postnatal pathology in infants with antenatal hydronephrosis. Our objective was to review the current literature to determine whether the degree of antenatal hydronephrosis and related antenatal ultrasound findings are associated with postnatal outcome. We searched Medline (1966-2005), Embase (1991-2004), and the Cochrane Library databases for articles on antenatal hydronephrosis. We required studies to have subjects selected on the basis of documented measurements of antenatal hydronephrosis and followed to a postnatal diagnosis. We excluded case reports, review articles, and editorials. Two independent investigators extracted data. We screened 1645 citations, of which 17 studies met inclusion criteria. We created a data set of 1308 subjects. The risk of any postnatal pathology per degree of antenatal hydronephrosis was 11.9% for mild, 45.1% for moderate, and 88.3% for severe. There was a significant increase in risk per increasing degree of hydronephrosis. The risk of vesicoureteral reflux was similar for all degrees of antenatal hydronephrosis. The findings of this meta-analysis can potentially be used for prenatal counseling and may alter current postnatal management of children with antenatal hydronephrosis. Overall, children with any degree of antenatal hydronephrosis are at greater risk of postnatal pathology as compared with the normal population. Moderate and severe antenatal hydronephrosis have a significant risk of postnatal pathology, indicating that comprehensive postnatal diagnostic management should be performed. Mild antenatal hydronephrosis may carry a risk for postnatal pathology, but additional prospective studies are needed to determine the optimal management of these children. A well-defined prospective analysis is needed to further define the risk of pathology and the appropriate management protocols.
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            Outcome of isolated antenatal hydronephrosis: a prospective cohort study.

            The purpose of this study was to report the outcome of infants with antenatal hydronephrosis. Between May 1999 and June 2006, all patients diagnosed with isolated fetal renal pelvic dilatation (RPD) were prospectively followed. The events of interest were: presence of uropathy, need for surgical intervention, RPD resolution, urinary tract infection (UTI), and hypertension. RPD was classified as mild (5-9.9 mm), moderate (10-14.9 mm) or severe (>or=15 mm). A total of 192 patients was included in the analysis; 114 were assigned to the group of non-significant findings (59.4%) and 78 to the group of significant uropathy (40.6%). Of 89 patients with mild dilatation, 16 (18%) presented uropathy. Median follow-up time was 24 months. Twenty-seven patients (15%) required surgical intervention. During follow-up, UTI occurred in 27 (14%) children. Of 89 patients with mild dilatation, seven (7.8%) presented UTI during follow-up. Renal function, blood pressure, and somatic growth were within normal range at last visit. The majority of patients with mild fetal RPD have no significant findings during infancy. Nevertheless, our prospective study has shown that 18% of these patients presented uropathy and 7.8% had UTI during a medium-term follow-up time. Our findings suggested that, in contrast to patients with moderate/severe RPD, infants with mild RPD do not require invasive diagnostic procedures but need strict clinical surveillance for UTI and progression of RPD.
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              Urinary tract dilatation in utero: classification and clinical applications.

              A morphologic classification of in utero urinary tract dilatation is presented. Ninety-two hydronephrotic fetal kidneys diagnosed with ultrasound were graded according to the proposed classification. The findings suggest that grade I dilatation (anteroposterior diameter of the renal pelvis less than 10 mm) should be considered normal. Grades II and III constitute an intermediate hydronephrosis, requiring postnatal urologic surgery in nearly half the cases. Grade IV (moderate dilatation of the calyces, with easily identified residual renal cortex) and grade V (severe dilatation of the calyces with atrophic cortex) are clearly pathologic and require neonatal corrective surgery. It is hoped that use of this simple and practical classification will facilitate communication and comparison of results in the literature.
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                Author and article information

                Contributors
                Role: ND
                Journal
                ped
                Revista Cubana de Pediatría
                Rev Cubana Pediatr
                Editorial Ciencias Médicas (Ciudad de la Habana )
                1561-3119
                March 2012
                : 84
                : 1
                : 80-91
                Affiliations
                [1 ] Hospital Pediátrico William Soler Cuba
                Article
                S0034-75312012000100009
                c1357fa8-e20a-4783-a498-7238505d63d0

                http://creativecommons.org/licenses/by/4.0/

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                SciELO Cuba

                Self URI (journal page): http://scielo.sld.cu/scielo.php?script=sci_serial&pid=0034-7531&lng=en
                Categories
                PEDIATRICS

                Pediatrics
                high urinary tract dilatation,pyelectasia,hydronephrosis,vesicoureteral reflux,dilatación del tracto urinario superior,pielectasia,hidronefrosis,reflujo vesicoureteral

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