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      Influenza-Associated Mortality in Georgia (2009–2011)

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          Abstract

          We analyzed data from NCDCPH Georgia where samples from outpatients with influenza-like illness (ILI) and inpatients with severe acute respiratory syndrome (SARI) are referred for testing on influenza virus using PCR analysis. During 2009-2010 and 2010-2011 influenza pandemics total number of the laboratory-confirmed influenza cases were 1286 with 33 deaths (all of them influenza type A) and 1203 (51.4% type A) with 44 deaths, respectively. At least one underlying medical condition was reported in 70.7% (for pandemic influenza strain) and 96% (for influenza type B) of deaths. Predominating preexisting condition was coronary heart disease.

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          Estimates of the Prevalence of Pandemic (H1N1) 2009, United States, April–July 2009

          Carrie Reed, Frederick J. Angulo, David Swerdlow … (2009)
          Through July 2009, a total of 43,677 laboratory-confirmed cases of influenza A pandemic (H1N1) 2009 were reported in the United States, which is likely a substantial underestimate of the true number. Correcting for under-ascertainment using a multiplier model, we estimate that 1.8 million–5.7 million cases occurred, including 9,000–21,000 hospitalizations.
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            Hospitalized patients with 2009 pandemic influenza A (H1N1) virus infection in the United States--September-October 2009.

            Lesley Bullion, Jacek Skarbinski, Jennifer Lee … (2011)
            Given the potential worsening clinical severity of 2009 pandemic influenza A (H1N1) virus (pH1N1) infection from spring to fall 2009, we conducted a clinical case series among patients hospitalized with pH1N1 infection from September through October 2009. A case patient was defined as a hospitalized person who had test results positive for pH1N1 virus by real-time reverse-transcription polymerase chain reaction. Among 255 hospitalized patients, 34% were admitted to an intensive care unit and 8% died. Thirty-four percent of patients were children <18 years of age, 8% were adults ≥ 65 years of age, and 67% had an underlying medical condition. Chest radiographs obtained at hospital admission that had findings that were consistent with pneumonia were noted in 103 (46%) of 255 patients. Among 255 hospitalized patients, 208 (82%) received neuraminidase inhibitors, but only 47% had treatment started ≤ 2 days after illness onset. Overall, characteristics of hospitalized patients with pH1N1 infection in fall 2009 were similar to characteristics of patients hospitalized with pH1N1 infection in spring 2009, which suggests that clinical severity did not change substantially over this period.
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              Drug use and pregnancy - challenges for public health.

              V. Gyarmathy, B Guarita, L Montanari … (2009)
              Involving pregnant drug users in drug treatment is likely to decrease the chances of pre- and perinatal complications related to drug use and to increase access to prenatal care. Timely medical intervention can effectively prevent vertical transmission of human immunodeficiency virus, hepatitis B virus as well as certain other sexually transmitted diseases, and would allow newborns infected with hepatitis C virus during birth to receive immediate treatment.
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                Author and article information

                Journal
                Journal ID (nlm-ta): Influenza Res Treat
                Journal ID (iso-abbrev): Influenza Res Treat
                Journal ID (publisher-id): IRT
                Title: Influenza Research and Treatment
                Publisher: Hindawi Publishing Corporation
                ISSN (Print): 2090-1380
                ISSN (Electronic): 2090-1399
                Publication date (Print): 2012
                Publication date (Electronic): 15 August 2012
                Volume: 2012
                Electronic Location Identifier: 480763
                Affiliations
                National Center for Disease Control and Public Health, 9 Asatiani Street 0177 Tbilisi, Georgia
                Author notes

                Academic Editor: Zichria Zakay-Rones

                Article
                DOI: 10.1155/2012/480763
                PMC ID: 3447290
                PubMed ID: 23074667
                SO-VID: c1442018-7eb6-4bbb-91a3-b2331cfb3b98
                Copyright statement: Copyright © 2012 Maia Butsashvili et al.
                License:

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 24 April 2012
                Date revision received : 7 July 2012
                Date accepted : 9 July 2012
                Categories
                Subject: Research Article

                ScienceOpen disciplines: Infectious disease & Microbiology
                Data availability:
                ScienceOpen disciplines: Infectious disease & Microbiology

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