For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
39
views
210
references
 Top references
cited by
18
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      175
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics

      review-article
      Author(s):   1 , 1 , 1 , 2 ,
      Publication date (Electronic):
      Journal: BMC Biology
      Publisher: BioMed Central

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Animal domestication has fascinated biologists since Charles Darwin first drew the parallel between evolution via natural selection and human-mediated breeding of livestock and companion animals. In this review we show how studies of ancient DNA from domestic animals and their wild progenitors and congeners have shed new light on the genetic origins of domesticates, and on the process of domestication itself. High-resolution paleogenomic data sets now provide unprecedented opportunities to explore the development of animal agriculture across the world. In addition, functional population genomics studies of domestic and wild animals can deliver comparative information useful for understanding recent human evolution.

          Related collections

          Most cited references210

          • Record: found
          • Abstract: found
          • Article: not found

          The complete genome sequence of a Neandertal from the Altai Mountains

          Kay Prüfer, Fernando Racimo, Nick Patterson … (2014)
          We present a high-quality genome sequence of a Neandertal woman from Siberia. We show that her parents were related at the level of half siblings and that mating among close relatives was common among her recent ancestors. We also sequenced the genome of a Neandertal from the Caucasus to low coverage. An analysis of the relationships and population history of available archaic genomes and 25 present-day human genomes shows that several gene flow events occurred among Neandertals, Denisovans and early modern humans, possibly including gene flow into Denisovans from an unknown archaic group. Thus, interbreeding, albeit of low magnitude, occurred among many hominin groups in the Late Pleistocene. In addition, the high quality Neandertal genome allows us to establish a definitive list of substitutions that became fixed in modern humans after their separation from the ancestors of Neandertals and Denisovans.
          Article 0 comments Cited 834 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            A high-coverage genome sequence from an archaic Denisovan individual.

            Matthias Meyer, Martin Kircher, Marie-Theres Gansauge … (2012)
            We present a DNA library preparation method that has allowed us to reconstruct a high-coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The quality of this genome allows a direct estimation of Denisovan heterozygosity indicating that genetic diversity in these archaic hominins was extremely low. It also allows tentative dating of the specimen on the basis of "missing evolution" in its genome, detailed measurements of Denisovan and Neandertal admixture into present-day human populations, and the generation of a near-complete catalog of genetic changes that swept to high frequency in modern humans since their divergence from Denisovans.
            Article 0 comments Cited 780 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Genomic insights into the origin of farming in the ancient Near East

              Iosif Lazaridis, Dani Nadel, Gary Rollefson … (2016)
              We report genome-wide ancient DNA from 44 ancient Near Easterners ranging in time between ~12,000-1,400 BCE, from Natufian hunter-gatherers to Bronze Age farmers. We show that the earliest populations of the Near East derived around half their ancestry from a ‘Basal Eurasian’ lineage that had little if any Neanderthal admixture and that separated from other non-African lineages prior to their separation from each other. The first farmers of the southern Levant (Israel and Jordan) and Zagros Mountains (Iran) were strongly genetically differentiated, and each descended from local hunter-gatherers. By the time of the Bronze Age, these two populations and Anatolian-related farmers had mixed with each other and with the hunter-gatherers of Europe to drastically reduce genetic differentiation. The impact of the Near Eastern farmers extended beyond the Near East: farmers related to those of Anatolia spread westward into Europe; farmers related to those of the Levant spread southward into East Africa; farmers related to those from Iran spread northward into the Eurasian steppe; and people related to both the early farmers of Iran and to the pastoralists of the Eurasian steppe spread eastward into South Asia.
              Article 0 comments Cited 374 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Contributors
                David E. MacHugh: david.machugh@ucd.ie
                Journal
                Journal ID (nlm-ta): BMC Biol
                Journal ID (iso-abbrev): BMC Biol
                Title: BMC Biology
                Publisher: BioMed Central (London )
                ISSN (Electronic): 1741-7007
                Publication date (Electronic): 2 December 2019
                Publication date PMC-release: 2 December 2019
                Publication date Collection: 2019
                Volume: 17
                Electronic Location Identifier: 98
                Affiliations
                [1 ]ISNI 0000 0001 0768 2743, GRID grid.7886.1, Animal Genomics Laboratory, , UCD School of Agriculture and Food Science, University College Dublin, ; Dublin, D04 V1W8 Ireland
                [2 ]ISNI 0000 0001 0768 2743, GRID grid.7886.1, UCD Conway Institute of Biomolecular and Biomedical Research, , University College Dublin, ; Dublin, D04 V1W8 Ireland
                Article
                Publisher ID: 724
                DOI: 10.1186/s12915-019-0724-7
                PMC ID: 6889691
                PubMed ID: 31791340
                SO-VID: c1590314-8c19-4e15-be1a-d7da0c5de2f1
                Copyright © © The Author(s). 2019
                License:

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                Date received : 13 November 2019
                Date accepted : 13 November 2019
                Categories
                Subject: Review
                Custom metadata
                issue-copyright-statement © The Author(s) 2019

                ScienceOpen disciplines: Life sciences
                Data availability:
                ScienceOpen disciplines: Life sciences

                Comments

                Comment on this article

                scite_

                Similar content175

                See all similar

                Cited by17

                See all cited by