Epidemiological characteristics of pulmonary tuberculosis among students in Wuhan from 2011 to 2020

Abstract

Objective To analyze the epidemiological characteristics of pulmonary tuberculosis among students in Wuhan from 2011 to 2020, and to provide a basis for the scientific development of interventions and strategies.

Methods Epidemiological distribution, time of onset and treatment, as well as treatment outcomes of student tuberculosis in Wuhan from 2011 to 2020 registered in the national tuberculosis inlonnation management system were described.

Results During 2011-2020, 4 337 student tuberculosis patients in Wuhan were registered. The average annual incidence rate was 22.44/10 million, and the annual decreasing rate of 7.86%. The incidence of male and female patients was 1.76:1, and the incidence rate of male was higher than that of female (χ ² = 184.18, P<0.01). Most of patients aged 19-22 years old, accounting for 47.89%; Tuberculosis reports were highest during March to May, and September to November, and lowest during January to February, and July to August. Student patients were mainly concentrated in Hongshan District, Jiangxia District and Wuchang District, where schools were more distributed in Hongshan District, Dongxihu District, Wuchang District and Xinzhou District. The median duration from tuberculosis onset to treatment was 9(3, 21) days, which varied significantly by region, age, nationality, and patient residence ( Z = −9.25, 47.14, 9.88, 43.96, P<0.01). The treatment and outcome of student tuberculosis patients were varied significantly by year and nationality ( P<0.05).

Conclusion The incidence of student tuberculosis in Wuhan City showed a slow downward trend. Most of student tuberculosis are college and high school students. Time and place of case detection are relatively fixed. The time of treatment and the outcome of treatment vary significantly. Tuberculosis prevention and control strategies should be formulated according to the local conditions according to the tuberculosis distribution characteristics, as well as enhancing surveillance, health promotion, active discovery and supervision management of tuberculosis in school settings.

Abstract

【摘要】 目的分析2011—2020年武汉市学生肺结核流行特征, 为科学制定干预策略和措施提供依据。 方法 对国家结 核病管理信息系统登记的2011—2020年武汉市学生结核病病案信息数据进行分布特征、发病就诊时间、治疗转归情况的 统计分析。 结果 2011—2020年武汉市登记学生肺结核患者4 337例, 年均登记发病率为22.44/10万, 年均递降率为 7.86%;男女发病数比为1.76:1, 男生发病率髙于女生(χ ² = 184.18, P<0.01);发病年龄以19~22岁组最髙, 占47.89%；每 年报告发病髙峰是3—5月和9一11月, 发病低谷是每年1—2月和7—8月；学生患者主要集中在学校分布较多的洪山区、 江夏区和武昌区, 学校聚集性疫情频发于洪山区、东西湖区、武昌区和新洲区;学生患者发病至就诊求医时间 M ( P ₂₅, P ₇₇) 为9(3, 21)d, 按地区、年龄、民族和患者来源分组组间差异均有统计学意义( Z值分别为 −9.25, 47.14, 9.88, 43.96, P 值均<0.01);学生患者治疗与转归按年份、民族分组组间差异均有统计学意义( P值均<0.05)。 结论 武汉市学生肺结核疫情呈 缓慢波动下降趋势, 年龄段以大学生和髙中生为主, 集中发现时间和地点相对固定, 病例就诊时间和治疗转归各有区别。 应根据各区县学生分布特点因时因地分类地制定防控策略, 加强疫情监测、健康促进、主动发现和督导管理。