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      The epidemiology of osteoarthritis.

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          Abstract

          Osteoarthritis (OA) is a leading cause of disability and its incidence is rising due to increasing obesity and an ageing population. Risk factors can be divided into person-level factors, such as age, sex, obesity, genetics, race/ethnicity and diet, and joint-level factors including injury, malalignment and abnormal loading of the joints. The interaction of these risk factors is complex and provides a challenge to the managing physician. The purpose of this review is to illustrate how each of these factors interact together to instigate incident OA as well as to outline the need for ongoing epidemiologic studies for the future prevention of both incident and progressive OA. It is only by understanding the impact of this disease and the modifiable risk factors that we will be able to truly target public health prevention interventions appropriately.

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          Author and article information

          Journal
          Best Pract Res Clin Rheumatol
          Best practice & research. Clinical rheumatology
          1532-1770
          1521-6942
          Feb 2014
          : 28
          : 1
          Affiliations
          [1 ] Sydney Medical School, University of Sydney, Sydney, NSW, Australia. Electronic address: vjoh6545@uni.sydney.edu.au.
          [2 ] Rheumatology Department, Royal North Shore Hospital and Kolling Institute, University of Sydney, Sydney, NSW, Australia. Electronic address: David.Hunter@sydney.edu.au.
          Article
          S1521-6942(14)00005-9
          10.1016/j.berh.2014.01.004
          24792942
          Copyright © 2014 Elsevier Ltd. All rights reserved.

          Aetiology, Epidemiology, Osteoarthritis

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