Contributors
Hugo G. Hilton:
ORCID: http://orcid.org/0000-0003-1488-7194
Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Project administrationRole:
ValidationRole: VisualizationRole: Writing – original draftRole: Writing – review
& editing
Nimrod D. Rubinstein:
ORCID: http://orcid.org/0000-0002-0779-2843
Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
ValidationRole: VisualizationRole: Writing – original draftRole: Writing – review
& editing
Peter Janki: Role: Investigation
Andrea T. Ireland: Role: Resources
Nicholas Bernstein:
ORCID: http://orcid.org/0000-0001-9685-0998
Role: Methodology
Nicole L. Fong: Role: Formal analysis
Kevin M. Wright: Role: Investigation
Megan Smith: Role: InvestigationRole: Resources
David Finkle: Role: InvestigationRole: Resources
Baby Martin-McNulty: Role: Resources
Margaret Roy: Role: Resources
Denise M. Imai: Role: Investigation
Vladimir Jojic: Role: Investigation
Rochelle Buffenstein:
ORCID: http://orcid.org/0000-0003-3285-8311
Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Project administrationRole:
ResourcesRole: SupervisionRole: Writing – original draftRole: Writing – review & editing
Avinash Bhandoola: Role: Academic Editor
Journal
Journal ID (nlm-ta): PLoS Biol
Journal ID (iso-abbrev): PLoS Biol
Journal ID (publisher-id): plos
Journal ID (pmc): plosbiol
Title:
PLoS Biology
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1544-9173
ISSN
(Electronic):
1545-7885
Publication date
(Electronic):
21
November
2019
Publication date Collection:
November
2019
Publication date PMC-release: 21
November
2019
Volume: 17
Issue: 11
Electronic Location Identifier: e3000528
Affiliations
[1
]
Calico Life Sciences LLC, South San Francisco, California, United States of America
[2
]
Comparative Pathology Laboratory, School of Veterinary Medicine, University of California,
Davis, Davis, California, United States of America
National Cancer Institute, UNITED STATES
Author notes
I have read the journal's policy and the authors of this manuscript have the following
competing interests: NDR, ATI, NB, NLF, KMW, MS, BM-M, MR, VJ, RB, HGH, PJ, and DF
were employees of Calico Life Sciences at the time that the study was undertaken.
Author information
Article
Publisher ID:
PBIOLOGY-D-19-02468
DOI: 10.1371/journal.pbio.3000528
PMC ID: 6894886
PubMed ID: 31751331
SO-VID: c1b2268b-700a-4d2c-9dc7-757d8772d914
Copyright © © 2019 Hilton et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 23
August
2019
Date
accepted
: 7
November
2019
Page count
Figures: 3,
Tables: 0,
Pages: 32
Funding
Funded by: Calico LLC
Award ID: 1111
Award Recipient
:
ORCID: http://orcid.org/0000-0003-3285-8311
Rochelle Buffenstein
All authors of this manuscript, HGH, NDR, PJ, ATI, NB, NLF, KMW, MS, DF, BM-M, MR,
DMI, VJ, and RB, as well as this work itself, have been entirely funded by Calico
Life Sciences. The funders approved performing the study and its publication.
Categories
Subject:
Short Reports
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Spleen
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Spleen
Subject:
Biology and life sciences
Subject:
Cell biology
Subject:
Cellular types
Subject:
Animal cells
Subject:
Blood cells
Subject:
White blood cells
Subject:
NK cells
Subject:
Biology and life sciences
Subject:
Cell biology
Subject:
Cellular types
Subject:
Animal cells
Subject:
Immune cells
Subject:
White blood cells
Subject:
NK cells
Subject:
Biology and life sciences
Subject:
Immunology
Subject:
Immune cells
Subject:
White blood cells
Subject:
NK cells
Subject:
Medicine and health sciences
Subject:
Immunology
Subject:
Immune cells
Subject:
White blood cells
Subject:
NK cells
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Marker Genes
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Marker Genes
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Animal Models
Subject:
Naked Mole Rats
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Mammals
Subject:
Rodents
Subject:
Naked Mole Rats
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Animal Genomics
Subject:
Mammalian Genomics
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Neutrophils
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Neutrophils
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Neutrophils
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Neutrophils
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
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