SYSTEMIC will reach a break-through to re-enter recovered nutrients from organic waste into the agricultural system closing the nutrient cycle. Consequently, this will offer solutions for pressing environmental issues and to reduce the import of phosphorus (P) as finite irreplaceable essential resource now sourced from mines. The SYSTEMIC project aims to shift the European biomass treatment practice to the next level. Departing from existing business cases and a new ground-breaking large scale demonstration plant, the future of anaerobic digestion (AD) value chains will be investigated and demonstrated. The result will help existing and future AD-operators to maximise their performance: produce and sell more quality products, generate more energy and be independent on subsidies. By the market driven leadership, the SYSTEMIC-project will finally turn biomass waste and residues into valuable products while reducing water pollution, greenhouse gas emission and creating quality jobs in rural areas. The five demonstration plants will allow innovative combinations of modules to elaborate possible optimisations for increasing the production quantity and quality of new mineral products, and the integration of these products into a circular economy. The experiences from the demonstration plants will be used to evaluate another 10 cases in different members states. The systemic innovations deals with (a) an end-user driven approach (b) specific technical developments on nutrient recovery, (c) cost efficient investigation of real-world circular economy business cases, and (d) proposed solutions for operational, regulatory and institutional barriers. Using partial funding from the European Commission, the SYSTEMIC industry-driven consortium will validate for the first time the technical and economic viability of a fully integrated, multistep approach in an operational environment. The successful practical demonstration will put the European sector in a leading position to offer efficient mineral recovery technologies.