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      Disclosure of HIV status and adherence to daily drug regimens among HIV-infected children in Uganda.

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          Abstract

          Pediatric adherence to daily drug regimens has not been widely assessed in Africa where majority of HIV infected children live. Using in-depth interviews of 42 HIV-infected children taking ART and/or cotrimoxazole prophylaxis, and 42 primary caregivers, at a comprehensive HIV/AIDS clinic in Uganda, we evaluated their adherence experiences for purposes of program improvement. Daily drug regimens provided by the pediatric clinic included cotrimoxazole prophylaxis as well as ART and cotrimoxazole combined. Complete disclosure of HIV status by caregivers to children and strong parental relationships were related to good adherence. Structural factors including poverty and stigma were barriers to adherence even for children who had had complete disclosure and a supportive relationship with a parent. To ensure adherence to life-extending medications, our findings underscore the need for providers to support caregivers to disclose, provide on-going support and maintain open communication with HIV-infected children taking cotrimoxazole prophylaxis and ART.

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          Author and article information

          Journal
          AIDS Behav
          AIDS and behavior
          Springer Science and Business Media LLC
          1090-7165
          1090-7165
          Jul 2006
          : 10
          : 4 Suppl
          Affiliations
          [1 ] CDC-Uganda, Global AIDS Program, Kampala, Uganda. wmb8@ug.cdc.gov
          Article
          10.1007/s10461-006-9141-3
          16791525
          c203d1d0-1ef1-46a5-843b-344b3952ff56
          History

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