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      Trombose venosa profunda de membros inferiores em pacientes com covid-19 Translated title: Deep vein thrombosis of lower limbs in patients with COVID-19

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          Abstract

          Resumo Com o avanço do conhecimento, a covid-19 passou a ser considerada uma doença do sistema respiratório, podendo ter comprometimento multissistêmico. Analisou-se a prevalência de trombose venosa profunda (TVP) em membros inferiores em pacientes acometidos pela covid-19 através de uma pesquisa de revisão integrativa, considerando o período de 2019 a 2022. Os procedimentos utilizados para a seleção dos artigos foram identificação das palavras-chave, elaboração da estratégia de busca, consulta em bases de dados e exclusão dos artigos em duplicata e outros. A exclusão foi feita com base nos seguintes critérios: artigos sobre complicações vasculares arteriais em membros inferiores, pesquisas laboratoriais, relatos de casos referentes a complicações venosas e arteriais em outros sítios e artigos não relacionados ao desfecho de TVP. Do total de 284 artigos, foram incluídos 42. Observou-se grande variabilidade na prevalência de TVP em pacientes com covid-19 (0,43 a 60,87%). Sugere-se que a ocorrência de TVP em pacientes com covid-19 está associada à gravidade desta doença.

          Translated abstract

          Abstract As knowledge has accumulated, COVID-19 has come to be considered a disease of the respiratory system that can also cause multisystemic involvement. This study analyzed the prevalence of deep venous thrombosis (DVT) in the lower limbs of patients with COVID-19 by conducting an integrative review of the literature published from 2019 to 2022. The procedures involved in article selection were identification of keywords, definition of the search strategy, consultation of databases, and exclusion of duplicate articles and others that did not meet the review objectives. Exclusion of articles was based on the following exclusion criteria: articles on arterial vascular complications involving the lower limbs, laboratory experiments, cases reports describing venous and arterial complications involving other sites, and articles unrelated to the outcome of interest: DVT. A total of 284 articles were identified, 42 of which were included. There was considerable variability in the prevalence of DVT among patients with COVID-19 (range: 0.43 to 60.87%). The findings suggest that occurrence of DVT in patients with COVID-19 is associated with disease severity.

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          Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19)

          Coronavirus has emerged as a global health threat due to its accelerated geographic spread over the last two decades. This article reviews the current state of knowledge concerning the origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19). Historically, it has caused two pandemics: severe acute respiratory syndrome and Middle East respiratory syndrome followed by the present COVID-19 that emerged from China. The virus is believed to be acquired from zoonotic source and spreads through direct and contact transmission. The symptomatic phase manifests with fever, cough and myalgia to severe respiratory failure. The diagnosis is confirmed using reverse transcriptase PCR. Management of COVID-19 is mainly by supportive therapy along with mechanical ventilation in severe cases. Preventive strategies form the major role in reducing the public spread of virus along with successful disease isolation and community containment. Development of a vaccine to eliminate the virus from the host still remains an ongoing challenge.
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            Extremely High Incidence of Lower Extremity Deep Venous Thrombosis in 48 Patients With Severe COVID-19 in Wuhan

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              Resolution of coronavirus disease 2019 (COVID-19)

              Coronavirus disease 2019 (COVID-19) was first detected in China in December, 2019, and declared as a pandemic by the World Health Organization (WHO) on March 11, 2020. The current management of COVID-19 is based generally on supportive therapy and treatment to prevent respiratory failure. The effective option of antiviral therapy and vaccination are currently under evaluation and development.
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                Author and article information

                Journal
                jvb
                Jornal Vascular Brasileiro
                J. vasc. bras.
                Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) (Porto Alegre, RS, Brazil )
                1677-5449
                1677-7301
                2023
                : 22
                : e20230027
                Affiliations
                [02] Araçatuba SP orgnameCentro Universitário Católico Auxilium Brasil
                [01] Botucatu orgnameUniversidade Estadual Paulista Brazil
                Article
                S1677-54492023000100404 S1677-5449(23)02200000404
                10.1590/1677-5449.202300271
                c2453741-1758-48a1-95cc-bbf822bd2e3d

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 13 July 2023
                : 19 April 2023
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 51, Pages: 0
                Product

                SciELO Brazil

                Categories
                Artigo de Revisão

                tromboembolia,anticoagulant,SARS-CoV-2,thromboembolism,anticoagulante

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