Expression of markers of endoplasmic reticulum stress-induced apoptosis in the placenta of women with early and late onset severe pre-eclampsia.

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Abstract

Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in severe pre-eclampsia (SPE) and is characterized by the activation of three signaling pathways: PKR-like endoplasmic reticulum kinase (PERK), activating transcription factor 6 (ATF6), and inositol-requiring 1 (Ire1). This study was designed to investigate the role of ER stress in the pathogenesis of SPE.

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Journal

Journal ID (iso-abbrev): Taiwan J Obstet Gynecol

Title: Taiwanese journal of obstetrics & gynecology

Publisher: Elsevier BV

ISSN (Electronic): 1875-6263

ISSN (Print): 1028-4559

Publication date (Electronic): Feb 2015

Volume: 54

Issue: 1

Affiliations

[1 ] Department of Obstetrics, Shandong Weifang People's Hospital, Weifang, China. Electronic address: Fujh_wfph@163.com.

[2 ] Department of Nephrology, The Second Hospital of Shandong University, Shandong University, Jinan, Shandong, China.

[3 ] Department of Obstetrics, Shandong Weifang People's Hospital, Weifang, China.

Article

Publisher Item ID: S1028-4559(14)00202-2

DOI: 10.1016/j.tjog.2014.11.002

PubMed ID: 25675914

SO-VID: c2a019a7-7fc5-4e19-a257-d15695400ec8

History

Keywords: endoplasmic reticulum stress,marker,pre-eclampsia

Data availability:

Keywords: endoplasmic reticulum stress, marker, pre-eclampsia

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