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      Risk factors and burden of osteoarthritis.

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          Abstract

          Osteoarthritis (OA) is one of the most common joint disorders worldwide. Its prevalence is increasing because of the growing aging of the population in developed and developing countries as well as an increase in risk factors leading to OA, particularly obesity and a sedentary lifestyle. Risk factors of OA can be divided into person-level factors (age, gender, obesity, genetics and diet) and joint-level factors (injury, malalignment and abnormal loading of the joints) that interact in a complex manner. OA is the 11th cause of disability in the world. It is responsible for activity limitations, particularly walking, and affects participation and quality of life. Patients with OA are at greater risk of all-cause mortality, particularly for cardiovascular diseases, than the general population. This excess mortality is closely associated with disability level. Consequently, strategies to reduce burden through primary and secondary prevention programs are increasingly important.

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          Author and article information

          Journal
          Ann Phys Rehabil Med
          Annals of physical and rehabilitation medicine
          Elsevier BV
          1877-0665
          1877-0657
          Jun 2016
          : 59
          : 3
          Affiliations
          [1 ] Service de rééducation et réadaptation de l'appareil locomoteur et des pathologies du rachis, université Paris Descartes, PRES Sorbonne Paris Cité, U1153, Inserm, hôpital Cochin, AP-HP, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France. Electronic address: clemence.palazzo@aphp.fr.
          [2 ] Service de rééducation et réadaptation de l'appareil locomoteur et des pathologies du rachis, université Paris Descartes, PRES Sorbonne Paris Cité, U1153, Inserm, hôpital Cochin, AP-HP, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France.
          Article
          S1877-0657(16)00024-5
          10.1016/j.rehab.2016.01.006
          26904959

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