32
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Loneliness and social isolation during the COVID-19 pandemic

      article-commentary

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Introduction The COVID-19 pandemic has led to implementation of unprecedented “social distancing” strategies crucial to limiting the spread of the virus. In addition to quarantine and isolation procedures for those who have been exposed to or infected with COVID-19, social distancing has been enforced amongst the general population to reduce the transmission of COVID-19. The risk of COVID-19 infection is greater for older adults over the age of 60 years who are at a heightened risk of severe illness, hospitalization, intensive care unit admission, and death (US CDC, 2020). According to the Centre for Evidence-Based Medicine, the case fatality rate (CFR) is about 4% for patients over 60 years old, 8% for patients over age 70 years, and approximately 15% for patients over the age of 80 (Oxford COVID-19 Evidence Service, 2020). This compares with CFR of 0.0026%–0.3% in those under age 45. However, there is a high cost associated with the essential quarantine and social distancing interventions for COVID-19, especially in older adults, who have experienced an acute, severe sense of social isolation and loneliness with potentially serious mental and physical health consequences. The impact may be disproportionately amplified in those with pre-existing mental illness, who are often suffering from loneliness and social isolation prior to the enhanced distancing from others imposed by the COVID-19 pandemic public health measures. Older adults are also more vulnerable to social isolation and loneliness as they are functionally very dependent on family members or supports by community services. While robust social restrictions are necessary to prevent spread of COVID-19, it is of critical importance to bear in mind that social distancing should not equate to social disconnection. The present position paper aims to describe the nature of loneliness and social isolation among older persons, its effect on their health, and ways to cope with loneliness and social isolation during the COVID-19 pandemic. Loneliness and social isolation Loneliness and social isolation frequently co-occur and are all too common in older adults. While the term loneliness refers to subjective feelings, social isolation is defined by the level and frequency of one’s social interactions. As a generally accepted concept, loneliness is defined as the subjective feeling of being alone, while social isolation describes an objective state of individuals’ social environments and interactional patterns. Studies suggest that while loneliness and social isolation are not equal to each other, both can exert a detrimental effect on health through shared and different pathways. Prior to the COVID-19 pandemic, loneliness and social isolation were so prevalent across Europe, the USA, and China (10–40%) (Leigh-Hunt et al., 2017; Xia and Li, 2018) that it was described as a “behavioral epidemic” (Jeste et al., 2020). The situation has only worsened with the restrictions imposed to contain viral spread. Physical and mental health impacts Loneliness is associated with various physical and mental repercussions, including elevated systolic blood pressure and increased risk for heart disease. Both loneliness and social isolation have been associated with an increased risk for coronary artery disease-associated death, even in middle-aged adults without a prior history of myocardial infarction (Heffner et al., 2011; Steptoe et al., 2013). Furthermore, research has shown that both loneliness and social isolation are independent risk factors for higher all-cause mortality (Yu et al., 2020). Being lonely has several adverse impacts on mental health. Reduced time in bed spent asleep (7% reduced sleep efficiency) and increased wake time after sleep onset have been related to loneliness (Cacioppo et al., 2002; Fässberg et al., 2012). Increased depressive symptomatology may also be caused by loneliness, along with poor self-rated health, impaired functional status, vision deficits, and a perceived negative change in the quality of one’s life (Lee et al., 2019). A systematic review of suicide risk also found that loneliness is associated with both suicide attempts and completed suicide among older adults (Fässberg et al., 2012). Loneliness, along with depressive symptoms, are related to worsening cognition over time. A systematic review concluded that loneliness and social isolation were significantly associated with incident dementia (Kuiper et al., 2015). The proposed mechanism for the adverse health impacts of loneliness focuses on the physiological stress response (such as increased cortisol) (Xia and Li, 2018). Abnormal stress responses lead to adverse health outcomes. For social isolation, the mechanism may be related to behavioral changes, including an unhealthy lifestyle (such as smoking, alcohol consumption, lower physical activity, poor dietary choices, and noncompliance with medical prescription) (Kobayashi and Steptoe, 2018; Leigh-Hunt et al., 2017). A smaller social network with less medical support exacerbates these conditions. Recognizing and developing a better understanding of these possible mechanisms should help us to design the most impactful interventions. Tips for preventing the detrimental effect of loneliness and social isolation There are established ways to maintain feelings of being connected to others despite having to maintain social distancing. By organizing our activities every single day, we can become more resistant to the onset of feelings of loneliness. For older adults, some tips are as follows. Keep connections Spend more time with your family. Utilize opportunities offered by the pandemic. Before the pandemic, some family members may have been distracted by work and school commitments, but now they may have more time at home and a higher degree of freedom to connect with older loved ones. In the era of social distancing, quality interactions using physical distancing of at least two meters along with the use of personal protective equipment such as masks enable contact with family members. This is vitally helpful to defend against loneliness. Maintain social connections with technology. Along with the telephone, technology has changed the way people interact with each other. Social media platforms such as Facebook, Skype, Twitter, LINE, and Instagram enable people to stay connected in a variety of ways. Many older adults, however, may not be as familiar with these new technologies, and this style of interaction may not effectively serve their emotional needs. We can help older family members and friends to overcome such technology barriers. Online video chat is easier to use and sufficiently conveys nonverbal cues so that people can feel more engaged. Even without new technology available, communication through phone services is beneficial too. Conversations with a regular schedule through online or phone services with family members and loved ones can be helpful for older adults. Maintain basic needs and healthy activities Ensure basic needs are met. Family and carers should ensure food, medication, and mask accessibility for older adults, especially those who live alone. Structure every single day. To stay confined at home for much of every day is a psychological challenge for many people. When most outdoor activities are not available, it is not easy to maintain a regular daily schedule. However, we can encourage and support engagement with activities deemed pleasurable by the older person with benefits for physical, mental, and spiritual well-being. Regular scheduling is especially supportive for older people at risk of delirium, which is characterized by a disturbance of circadian rhythm. Television and YouTube channels adapted for older adults with proper physical and mental programs (e.g. exercise programs, mindfulness practice, and music programs) can also be very useful. Maintain physical and mental activities. Exercise has benefits for physical and psychological health (specifically for mood and cognition). There is evidence that regular engagement in mentally challenging and new activities may reduce the risk of dementia. Although we may not be able to exercise together as before, we should maintain physical activities at the individual level. Besides, these personal physical activities can be performed at a group level by setting a common goal, sharing our progress, or creating a friendly competition via social media. Pursue outdoor activities while following the guidance of social distancing. Brief outdoor activities are usually still possible and beneficial to health. One can feel much better as a result of sunlight exposure and the ability to see other people while still maintaining physical distancing. Manage emotions and psychiatric symptoms Manage cognition, emotion, and mood. Loneliness is often associated with negative thoughts (cognitions). Moreover, anxiety and depression may cause social withdrawal which will exacerbate the loneliness and isolation associated with social distancing. Acquiring reliable information about the pandemic helps avoid unnecessary worry and negative rumination. Conscious breathing, meditation, and other relaxation techniques are helpful for the mind and body and can decrease one’s level of anxiety and depression. Emotional support for family members and friends is especially important during this harsh pandemic period, but one should not hesitate to seek help as well. Pay attention to psychiatric symptoms. The pandemic is quite stressful for every individual, and the significant stress can precipitate the occurrence or recurrence of mental disorders in some people, especially vulnerable older people. Depression, anxiety, and sleep disturbance are common, especially when one is under quarantine or self-isolation. Other symptoms include anger, irritability, and compulsive behaviors, such as repeated washing and cleaning. Furthermore, the experiences of social isolation and quarantine may bring back post-traumatic stress disorder symptoms for those previously exposed to other related events such as the severe acute respiratory syndrome and Middle East respiratory syndrome epidemics (Hawryluck et al., 2004). Online screening tools and rating scales can help us to understand the magnitude of the impact on our mental health. People with existing psychiatric disorders and their family members should pay special attention to their mental health and follow important tips to prevent worsening of symptoms. Medical assistance should always be sought when necessary, particularly in response to the expression of suicidal ideation. Those taking prescribed psychiatric medications should make sure that their supply is adequate, despite the limitations imposed by social distancing and the difficulty in visiting the pharmacy. Government agencies, social service organizations, and healthcare providers should consider offering online psychological services (or at least phone services) to those psychogeriatric patients who need medical advice during the social isolation period. Take special care of older people with dementia and their family carers. The world and the way people live have significantly been disrupted in response to the COVID-19 pandemic. Changes are always stressful and require people to adapt. However, people with dementia have compromised adaptive function, and the pandemic may aggravate negative emotions and invoke behavioral and psychological symptoms. Recognizing that people with dementia may find it difficult to understand and comply with social distancing, caregivers should try to give instructions on hand hygiene, social distancing, and other protective measures in a simple, straightforward, and understandable way. Regular daily schedules and activities should be arranged and individually tailored to the dementia patient’s interests. Family carers might be under especially severe levels of stress and feel even more isolated and alone. More detailed information on the unique aspects of the pandemic’s effects on dementia caregiving is available on the Alzheimer’s Disease International website (Alzheimer’s Disease International, 2020). Conclusion The societal impact of the COVID-19 pandemic has been broad and very challenging. No aspect of normal societal functioning has been spared. Quarantine and social distancing are necessary measures to prevent the virus from spreading but also lead to elevated levels of loneliness and social isolation, which in turn produce physical- and mental-health related repercussions. Adopting appropriate steps to keep social and familial connections, maintain healthy activities, and manage emotions and psychiatric symptoms can help relieve the adverse consequences of loneliness and isolation. The pandemic has illuminated the pre-existing threat to well-being that older adults frequently experience with social isolation and loneliness. Perhaps we can use this moment to commit ourselves to addressing these unfortunate aspects of life for older adults in the post-pandemic period, for example, developing virtual health care, new technology, and government policy. On the May 23, 2020, in collaboration with INTERDEM, IPA ran a webinar program addressing this very issue: “COVID-19, social distancing and its impact on social and mental health of the elderly population.”

          Related collections

          Most cited references12

          • Record: found
          • Abstract: found
          • Article: not found

          SARS Control and Psychological Effects of Quarantine, Toronto, Canada

          Severe acute respiratory syndrome (SARS) was contained globally by widespread quarantine measures, measures that had not been invoked to contain an infectious disease in North America for >50 years ( 1 – 6 ). Although quarantine has periodically been used for centuries to contain and control the spread of infectious diseases such as cholera and the plague with some success ( 1 – 4 , 6 – 8 ), the history of invoking quarantine measures is tarnished by threats, generalized fear, lack of understanding, discrimination, economic hardships, and rebellion ( 1 , 3 , 4 , 6 – 8 ). Quarantine separates persons who have been potentially exposed to an infectious agent (and thus at risk for disease) from the general community. For the greater public good, quarantine may create heavy psychological, emotional, and financial problems for some persons. To be effective, quarantine demands not only that at-risk persons be isolated but also that they follow appropriate infection control measures within their place of quarantine. Reporting on SARS quarantine has focused on ways in which quarantine was implemented and compliance was achieved ( 1 – 4 , 6 – 8 ). Adverse effects on quarantined persons and the ways in which those quarantined can best be supported have not been evaluated. Moreover, little is known about adherence to infection-control measures by persons in quarantine. Knowledge and understanding of the experiences of quarantined persons are critical to maximize infectious disease containment and minimize the negative effects on those quarantined, their families, and social networks. The objectives of our study were to assess the level of knowledge about quarantine and infection control measures of persons who were placed in quarantine, to explore ways by which these persons received information to evaluate the level of adherence to public health recommendations, and to understand the psychological effect on quarantined persons during the recent SARS outbreaks in Toronto, Canada. Methods Description of Quarantine in Toronto During the first and second SARS outbreaks in Toronto, >15,000 persons with an epidemiologic exposure to SARS were instructed to remain in voluntary quarantine (Health Canada, unpub. data). Data on the demographics of the quarantined population were collected, but have not yet been analyzed (B. Henry, Toronto Public Health, pers. comm.). Quarantined persons were instructed not to leave their homes or have visitors. They were told to wash their hands frequently, to wear masks when in the same room as other household members, not to share personal items (e.g., towels, drinking cups, or cutlery), and to sleep in separate rooms. In addition, they were instructed to measure their temperature twice daily. If any symptoms of SARS developed, they were to call Toronto Public Health or Telehealth Ontario for instructions ( 5 ). Study Population All persons who were placed in quarantine during the SARS outbreaks in Toronto (at least 15,000 persons) were eligible for participation in this study. The survey was announced through media releases, including locally televised interviews with the principal investigators. Information on the study and invitations to participate were posted in local healthcare institutions, libraries, and supermarkets. Ethics approval was obtained from the research ethics board of the University Health Network, a teaching institution affiliated with the University of Toronto. Survey Instrument A Web-based survey composed of 152 multiple choice and short- answer questions was to be completed after participants ended their period of quarantine. It took approximately 20 minutes to complete. Questions explored included the following: 1) knowledge and understanding of the reasons for quarantine ( 2 ), knowledge of and adherence to infection control directives, and ( 3 ) source of this knowledge. The psychological impact of quarantine was evaluated with validated scales, including the Impact of Event Scale—Revised (IES-R) ( 9 ) and the Center for Epidemiologic Studies—Depression Scale (CES-D) ( 10 ). The IES-R is a self-report measure designed to assess current subjective distress resulting from a traumatic life event and is composed of 22 items, each with a Likert rating scale from 0 to 4. The maximum score is 88. In a study of journalists working in war zones, the mean IES-R score of posttraumatic stress disorder (PTSD) was 20. In these persons, the presence of PTSD symptoms, as measured by this scale, was correlated with diagnostic psychiatric interviews ( 11 ). The CES-D is a measure of depressive symptoms composed of 20 self-report items, each with a Likert rating scale from 0 to 3. The maximum score is 60 ( 10 ). A score of> 16 has been shown to identify persons with depressive symptoms similar in severity to the levels observed among depressed patients ( 10 , 12 , 13 ). Open-ended questions provided respondents with the opportunity to relate the aspects of quarantine that were most difficult for them and allowed them to provide additional comments on their unique experiences. Statistical Analysis Means were calculated to summarize continuous variables. For categorical variables, group proportions were calculated. Student t tests were used to examine relationships between demographic variables and the psychological outcome variables, the scores on the IES-R and CES-D. A score of >20 on the IES-R was used to estimate the prevalence of PTSD symptoms ( 11 ). A score of >16 on the CES-D was used to estimate the prevalence of depressive symptoms ( 10 , 12 , 13 ). Analysis of variance (ANOVA), chi-square, and the Cochran-Armitage test for trend were used to examine relations between the IES-R and CES-D scores and the following independent variables: healthcare worker status, home or work quarantine, acquaintance of or direct exposure to someone with a diagnosis of SARS, combined annual household income, and the frequency with which persons placed in quarantine wore their masks. Linear regression for the trends between income categories and both PTSD and depressive symptoms was analyzed. The relationships between the IES-R and CES-D and whether persons in quarantine wore their masks all of the time versus never were examined by the Duncan-Waller K-ratio t tests. A p value of $75,000 (Canadian dollars [CAD]). Figure Number of persons in quarantine, Toronto, Canada, February 23–June 30, 2003. Figure courtesy of Toronto Public Health. The 129 respondents described 143 periods of quarantine with 90% of respondents being placed into quarantine only once; 66% of respondents were on home quarantine, while 34% were on work quarantine. The median duration of quarantine was 10 days (interquartile range 8–10 days). Half of respondents knew someone who was hospitalized with SARS of whom 77% were colleagues; 10% knew someone who had died of SARS (Table 1). Table 1 Characteristics of quarantined persons who responded to the survey Characteristic No. (%) N=129 Age (y) 18–25 11 (8.6) 26–35 37 (28.9) 36–45 44 (34.4) 46–55 21 (16.4) 56–65 11 (8.7) 66+ 4 (3.1) Marital status Married or common law 87 (68.0) Single or divorced 41 (32.0) Education High school 11 (9.2) College or university 109 (90.8) Income (Canadian $) $100,000 36 (34.0) Healthcare worker status No 40 (31.8) Yes 86 (68.3) Type of quarantine
(N = 143 episodes) Work 49 (34.3) Home 94 (65.7) Household members No. adults 1 28 (21.9) 2 72 (56.4) 3 22 (17.2) 4  5 (3.9) >5  1 (0.8) No. children 0 72 (55.8) 1 24 (18.6) 2 25 (19.4) 3 8 (6.2) Persons were notified of their need to go into quarantine from the following sources: their workplace (58%), the media (27%), their healthcare provider (7%), and public health officials (9%). Most (68%) understood that they were quarantined to prevent them from transmitting infection to others; 8.5% of respondents believed they were quarantined to protect themselves from infection; 15% did not believe they should have been placed into quarantine at all; and 8.5% provided more than one of these responses. The source of notification for quarantine influenced understanding of the reason for quarantine. Those who were notified by the media or their workplace were more likely to understand the reason for quarantine than those who were notified by their healthcare provider or public health unit (p = 0.04). Healthcare workers were also more likely to understand the reason for quarantine compared with non–healthcare workers, 76.5% versus 52.5% (p = 0.007). Combined household income and level of education did not influence understanding of the reason for quarantine. Information on Infection Control Measures Persons received their information regarding infection control measures to be adhered to during their quarantine from the following sources: the media (54%), public health authorities (52%), occupational health department (33%), healthcare providers (29%), word-of-mouth (23%), hospital Web sites (21%), and other Web sites (40%). Those who did not think they had been well-informed were angry that information on infection control measures and quarantine was inconsistent and incomplete, frustrated that employers (healthcare institutions) and public health officials were difficult to contact, disappointed that they did not receive the support they expected, and anxious about the lack of information on the modes of transmission and prognosis of SARS (Appendix). During the outbreaks, nearly 30% of respondents thought that they had received inadequate information about SARS. With respect to information regarding home infection control measures, 20% were not told with whom they could have contact; 29% did not receive specific instructions on when to change their masks; and 40%–50% did not receive instructions on the use and disinfection of personal items, including toothbrushes and cutlery; 77% were not given instructions regarding use and disinfection of the telephone. Healthcare worker status did not influence whether respondents thought they had received adequate information regarding any of the listed home infection control measures, except regarding the frequency of mask changing: healthcare workers more frequently reported that they had received adequate information, 78.8% versus 60.5% (p = 0.03). Adherence to Infection Control Measures Eighty-five percent of quarantined persons wore a mask in the presence of household members; 58% remained inside their residence for the duration of their quarantine. Thirty-three percent of those quarantined did not monitor their temperatures as recommended: 26% self-monitored their temperatures less frequently than recommended, and 7% did not measure their temperatures at all. No differences between healthcare workers and nonhealthcare workers were found with respect to adherence to recommended infection control measures. Psychological Impact of Quarantine The mean IES-R score was 15.2±17.8, and the mean CES-D was 13.0±11.6. The IES-R score was >20 for 28.9%; the CES-D score was >16 in 31.2% of quarantined persons (Table 2). The mean IES-R scores were not different for persons on home or work quarantine, 14.1±18.8 versus 17.6±16.6 (p = 0.33); the mean CES-D scores were also not different between the groups, 12.0±12.0 versus 15.2±10.7 (p = 0.16). Table 2 Prevalence of posttraumatic stress disorder and depressive symptoms according to patient demographicsa Characteristic No. (%) N=129 Prevalence CES-D 16 38 (31.2) IES-R 20 35 (28.9) Marital status Mean SD p value CES-D Single or divorced (n = 40) 12.9 10.7 0.85 Married (n = 79) 12.5 11.4 IES-R Single or divorced (n = 39) 14.5 16.6 0.82 Married (n = 79) 13.8 14.6 Income (Canadian $) CES-D $75,000 10.9  9.2 IES-R $75,000 11.8 11.6 Duration of quarantine (d) CES-D 10 17.0 14.2 IES-R 10 23.7 27.2 aCES-D, Center for Epidemiologic Studies—Depression Scale ( 10 ); IES-R,Impact of Event Scale—Revised ( 9 ).
bBy analysis of variance. The presence of PTSD symptoms was correlated with the presence of depressive symptoms (p $75,000 was associated with increased PTSD symptoms (mean IES-R score of 24.2±20.6 versus 20.0±24.4 versus 11.8±11.6, respectively) (p = 0.03 for the three-way comparison). Linear regression testing for trend over income categories was also significant (p = 0.01). A combined annual household income of CAD $75,000 was also associated with increased depressive symptoms (mean CES-D score of 18.3±15.4 versus 15.5±13.2 versus 10.9±9.2, respectively) (p = 0.05 for the three-way comparison) (Table 2). Results of linear regression testing for trend over income categories were also significant (p = 0.01). Neither age, level of education, healthcare worker status, living with other adult household members, nor having children was correlated with PTSD and depressive symptoms. The duration of quarantine was significantly related to increased PTSD symptoms, mean IES-R score of 23.7±27.2 for those in quarantine >10 days compared with 11.7±10.7 for those in quarantine 10 days versus 11.2±10.1 for those in quarantine 20 on the IES-R was used to estimate the prevalence of PTSD symptoms in our study population. This corresponds to the mean score measured on the IES-R in a study of journalists working in war zones that used diagnostic psychiatric interviews to confirm the presence of this disorder ( 11 ). Since most respondents to our survey were healthcare workers, we chose a work-related traumatic event for the comparison group. While other cutoff points may have been used to estimate the prevalence of PTSD symptoms in our population, the risk factors that we identified for increased PTSD symptoms, rather than the absolute prevalence of PTSD in our study participants, are the important findings of this study. This also applies to the risk factors that we identified for increased depressive symptoms in the respondents. Quarantined persons with risk factors for either PTSD or depressive symptoms may benefit from increased support from public health officials. In this population, the presence of PTSD symptoms was highly correlated with the presence of depressive symptoms even though different clinical symptoms characterize the two disorders. Kessler's National Comorbidity Study indicated a 48.2% occurrence of depression in patients with PTSD ( 15 ). PTSD is an anxiety disorder characterized by avoiding stimuli associated with a traumatic event, reexperiencing the trauma, and hyperarousal, such as increased vigilance ( 16 ). This disorder may develop after exposure to traumatic events that involve a life-threatening component, and a person's vulnerability to the development of PTSD can be increased if the trauma is perceived to be a personal assault ( 17 ). Increased length of time spent in quarantine was associated with increased symptoms of PTSD. This finding might suggest that quarantine itself, independent of acquaintance with or exposure to someone with SARS, may be perceived as a personalized trauma. The presence of more PTSD symptoms in persons with an acquaintance or exposure to someone with a diagnosis of SARS compared to persons who did not have this personal connection may indicate a greater perceived self-risk. The small number of respondents who were acquainted with or exposed to someone who died of SARS may explain the lack of correlation between this group and greater PTSD and depressive symptoms (44 persons died of SARS in the greater Toronto area). This study also notes the trend toward increasing symptoms of both PTSD and depression as the combined annual income of the respondent household fell from CAD >$75,000 to CAD 50% of the respondents reported a combined annual household income of CAD >$75,000. As many as 50% of respondents felt that they had not received adequate information regarding at least one aspect of home infection control, and not all of the respondents adhered to recommendations. Why some infection control measures were adhered to while others were not is unclear. A combination of lack of knowledge, an incomplete understanding of the rationale for these measures, and a lack of reinforcement from an overwhelmed public health system were likely contributors to this problem. Of particular interest, strictly adhering to infection control measures, including wearing masks more frequently than recommended, was associated with increased levels of distress. Whether persons with higher baseline levels of distress were more likely to strictly adhere to infection-control measures or whether adherence to recommended infection-control strategies resulted in developing higher levels of distress cannot be clarified without interviewing the respondents. Regardless of the cause, this distress may have been lessened with enhanced education and continued reinforcement of the rationale for these measures and outreach efforts to optimize coping with the stressful event. This study has several limitations. The actual number of respondents is low compared to the total number of persons who were placed into quarantine and therefore may not be representative of the entire group of quarantined persons. However, lack of funding, confidentiality of public health records, and an overloaded public health response system limited sampling in this study. Furthermore, a self-selection effect may have occurred with those persons who were experiencing the greatest or least levels of distress responding to the survey. In addition, respondents required access to a computer to respond, which suggests that they may be more educated and have higher socioeconomic status than the overall group who were quarantined. They also had to be English speaking. Recognizing these limitations, however, an anonymous Web-based method was chosen because concerns about persons' confidentiality precluded us from access to their public health records. A Web-based format was chosen over random-digit dialing for both cost considerations and time constraints. The project was initiated and completed without a funding source soon after the outbreak period at a time when concerns about SARS were still a part of daily life in Toronto. Obtaining as much information about the adverse effects of quarantine as close to the event as possible was important because a study conducted several months later would have been subject to the limitations of substantial recall bias. If this study were to be repeated, a study design ensuring a more representative selection of the population that used a combination of quantitative and qualitative methods, including structured diagnostic interviews, would be recommended to overcome these concerns. In the event of future outbreaks, a matched control group of persons who were not quarantined should be considered because it would allow an assessment of the distress experienced by the community at large. Finally, we determined only the prevalence of symptoms of PTSD and depression in our study population because these were the predominant psychological distresses that were observed to be emerging in our SARS patient population (W.L.G., pers. comm.). We also focused on symptoms of PTSD and depression because we believed that they would be the most likely to cause illness and interfere with long-term functioning. Future studies should assess persons for other psychological responses, including fear, anger, guilt, and stigmatization. A standardized survey instrument that considers the full spectrum of psychological responses to quarantine should be developed. In the event of future outbreaks in which quarantine measures are implemented, a standardized instrument would enable a comparison between the psychological responses to outbreaks of different infectious causes and could be used to monitor symptoms over time. Despite these limitations, the results of this survey allow for the generation of hypotheses that require further exploration. Our data show that quarantine can result in considerable psychological distress in the forms of PTSD and depressive symptoms. Public health officials, infectious diseases physicians, and psychiatrists and psychologists need to be made aware of this issue. They must work to define the factors that influence the success of quarantine and infection control practices for both disease containment and community recovery and must be prepared to offer additional support to persons who are at increased risk for the adverse psychological and social consequences of quarantine. Appendix Comments from survey respondents Unmet informational needs: 1. Public health /employers: a. Difficulty in access: "Called Public Health for 2 days. Got through 3 times; waited on hold for hours, then got hung up on." (respondent # 131) b. Failed expectations: "I was expecting someone from Public Health to check up on me but never got a call except on my last day of quarantine." (respondent #126); "Nobody told me anything. I was not contacted by health officials at all." (respondent# 99); "My employer should have been more forthcoming." (respondent #7); "I was not called by the hospital I worked at. I saw the quarantine on the news and spent a whole day trying to get through to my unit." (respondent #40) c. Lack of support: "I was looking for more support from the health care professionals. They left me in the dark to deal with this." (respondent #22) 2. Nature of information: a. Details re: infection control: "I have since learned that there are a lot of precautions that no one ever told me about." (respondent #81) b. Inconsistencies: "Information was not always the same. Many inconsistencies." (respondent #66) c. Timing: "Information was given too late, as I started 1 week after exposure. Unacceptable!" (respondent #27) d. Specific issues: i. Children: "Nobody can tell me exactly where my children would be arranged to go in case I got SARS myself. I was very panicked at that time and my husband was admitted that time because of the SARS." (respondent # 78) ii. Onset of symptoms: "What symptoms were considered serious and what to do when I experienced those symptoms." (respondent # 21); "I was mildly alarmed to realize that I didn't know what to do if I actually did develop symptoms of SARS." (respondent # 111) iii. Prognosis of SARS: "Most of the really important info is largely unknown" (respondent #53); "Prognosis for SARS, how many have recovered, what health problems recovered patients still have." (respondent #8I) iv. Mode of transmission: "If airborne what were the chances of contracting the disease… MD unable to answer." (respondent #90)
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            An overview of systematic reviews on the public health consequences of social isolation and loneliness

            Social isolation and loneliness have been associated with ill health and are common in the developed world. A clear understanding of their implications for morbidity and mortality is needed to gauge the extent of the associated public health challenge and the potential benefit of intervention.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found

              Social isolation, loneliness, and all-cause mortality in older men and women

              Both social isolation and loneliness are associated with increased mortality, but it is uncertain whether their effects are independent or whether loneliness represents the emotional pathway through which social isolation impairs health. We therefore assessed the extent to which the association between social isolation and mortality is mediated by loneliness. We assessed social isolation in terms of contact with family and friends and participation in civic organizations in 6,500 men and women aged 52 and older who took part in the English Longitudinal Study of Ageing in 2004-2005. A standard questionnaire measure of loneliness was administered also. We monitored all-cause mortality up to March 2012 (mean follow-up 7.25 y) and analyzed results using Cox proportional hazards regression. We found that mortality was higher among more socially isolated and more lonely participants. However, after adjusting statistically for demographic factors and baseline health, social isolation remained significantly associated with mortality (hazard ratio 1.26, 95% confidence interval, 1.08-1.48 for the top quintile of isolation), but loneliness did not (hazard ratio 0.92, 95% confidence interval, 0.78-1.09). The association of social isolation with mortality was unchanged when loneliness was included in the model. Both social isolation and loneliness were associated with increased mortality. However, the effect of loneliness was not independent of demographic characteristics or health problems and did not contribute to the risk associated with social isolation. Although both isolation and loneliness impair quality of life and well-being, efforts to reduce isolation are likely to be more relevant to mortality.
                Bookmark

                Author and article information

                Journal
                Int Psychogeriatr
                Int Psychogeriatr
                IPG
                International Psychogeriatrics
                Cambridge University Press (Cambridge, UK )
                1041-6102
                1741-203X
                26 May 2020
                : 1-4
                Affiliations
                [1 ]Department of Psychiatry, College of Medicine and National Taiwan University Hospital, National Taiwan University , Taipei, Taiwan
                [2 ]Department of Psychiatry, Faculty of Medicine, University of Ottawa , Ottawa, Canada
                [3 ]School of Psychiatry, University New South Wales; and Discipline Psychiatry, Sydney University , Sydney, Australia
                [4 ]Department of Psychiatry, Faculty of Medicine, University of Toronto , Toronto, Canada
                [5 ]Department of Psychiatry, Osaka University Graduate School of Medicine , Osaka, Japan
                Author notes
                Author information
                https://orcid.org/0000-0002-7934-7001
                Article
                S1041610220000988
                10.1017/S1041610220000988
                7306546
                32450943
                c2f9ecff-2491-436b-8912-1204e49553ad
                © International Psychogeriatric Association 2020

                This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 17 May 2020
                : 20 May 2020
                Page count
                References: 15, Pages: 4
                Categories
                Commentary

                Geriatric medicine
                Geriatric medicine

                Comments

                Comment on this article