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      Superposición del síndrome de intestino irritable y dispepsia funcional basados en criterios ROMA III en estudiantes de medicina de una universidad privada de Lima, Perú Translated title: Overlap of irritable bowel syndrome and functional dyspepsia based on Rome III criteria in medical students from a private university in Lima, Peru

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          Abstract

          Objetivos: Determinar la prevalencia de síndrome de intestino irritable y dispepsia funcional en estudiantes de medicina de una universidad privada en Lima, Perú. Asimismo, determinar los factores asociados a estas patologías. Material y métodos: Estudio de corte transversal observacional, descriptivo, retrospectivo. Se encuestó estudiantes de medicina de una universidad privada en Lima usando un cuestionario auto aplicado para trastornos funcionales Roma III y el cuestionario auto aplicado STEPwise para la definición de variables de consumo de alcohol y tabaco. Para el análisis de datos se usó el programa Stata 11.0. Resultados: De los 608 estudiantes, 543 respondieron el cuestionario. Se encontró una prevalencia de Síndrome de Intestino Irritable del 12,4%, de dispepsia del 16,9% y de ambas patologías simultáneamente, una prevalencia de 7,1%. El consumo de alcohol en la población total fue del 89,4% y de 29,0% de tabaco. Se encontró asociación entre ambas alteraciones (OR: 10,47, IC95% 5,08-21,55; p<0,001), dispepsia se asoció con sexo (OR: 0,16, IC95% 0,07-0,36 p<0,001), con consumo de alcohol (OR: 5,22, IC95% 1,13- 23,99 p=0,034) y con síndrome de intestino irritable (OR: 9,88, IC95% 4,78-20,46 p<0,001). Ambos trastornos en conjunto se asociaron con sexo (OR: 0,20, IC95% 0,06-0,60 p=0,004) y consumo diario de tabaco (OR: 3,23, IC95% 1,17-8,89 p=0,023). Conclusión: Se determinó una prevalencia de 12,4% de Síndrome de Intestino Irritable y 16,9% de dispepsia. Se reportó una superposición de estas patologías en 7,1%.

          Translated abstract

          Aims: To determine the prevalence of irritable bowel syndrome and functional dyspepsia in medical students from a private university in Lima, Peru. Furthermore, to determine the associated factors with these diseases. Material and methods: Observational descriptive and retrospective cross sectional study. Medical students from a private university in Lima were surveyed using a Rome III questionnaire for functional disorders and the STEPwise auto survey for defining the variables of alcohol and tobacco. For data analysis the Stata 11.0 program was used. Results: Of the 608 students, 543 answered the questionnaire. The prevalence of Irritable Bowel Syndrome was 12.4%, 16.9% of dyspepsia, and of both diseases simultaneously, a prevalence of 7.1% was found. Alcohol consumption in the total population was 89.4% and 29.0% of tobacco. Association between both disorders was found (OR 10.47, 95% CI 5.08 to 21.55; p <0.001), dyspepsia was associated with sex (OR: 0.16, 95% CI 0.07 to 0.36 p <0.001), with alcohol consumption (OR: 5.22, 95% CI 23.99 1,13- p = 0.034) and with irritable bowel syndrome (OR: 9.88, 95% CI 4.78 to 20.46 p <0.001). Both conditions together were associated with sex (OR: 0.20, 95% CI from 0.06 to 0.60 p = 0.004) and daily consumption of tobacco (OR: 3.23, 95% CI 1.17 to 8.89 p = 0.023). Conclusion: A prevalence of 12.4% of Irritable Bowel Syndrome and 16.9% of dyspepsia was determined. An overlap of 7.1% of these diseases was reported.

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          The functional gastrointestinal disorders and the Rome III process.

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            Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability over time.

            It has been suggested that irritable bowel syndrome (IBS) and functional dyspepsia represent the same disease entity, the irritable gut. The aim of this study was to test the stability, consistency, and relevance of the current classification in the entire, unselected population of persons with gastrointestinal and/or abdominal symptoms, including those who had not consulted physicians. Sequential postal questionnaires were sent to 1290 representative persons (age range, 20-79 years) sampled from the population. Questions were asked about the prevalence of 24 gastrointestinal and/or abdominal symptoms and the site and type of abdominal pain, if any. The prevalence of dyspepsia was 14% (32% if predominant reflux symptoms and concomitant IBS symptoms were included), and the prevalence of IBS was 12.5%. The 3-month incidence rates of reflux, dyspepsia, and IBS among previously symptomless persons were 0.5, 8, and 2 per 1000, respectively. Of persons with IBS, 87% also fulfilled the dyspepsia criteria, and the overlap between dyspepsia subgroups was more than 50%. The use of stricter criteria did not eliminate this overlap. Over a 1-year period, approximately 50% changed their symptom profile. Principal component analysis did not show any natural clustering of the symptoms. The separation of functional gastrointestinal symptoms into dyspepsia, its subgroups, and IBS may be inappropriate.
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              Epidemiology of functional dyspepsia: a global perspective.

              Dyspepsia refers to group of upper gastrointestinal symptoms that occur commonly in adults. Dyspepsia is known to result from organic causes, but the majority of patients suffer from non-ulcer or functional dyspepsia. Epidemiological data from population-based studies of various geographical locations have been reviewed, as they provide more realistic information. Population-based studies on true functional dyspepsia (FD) are few, due to the logistic difficulties of excluding structural disease in large numbers of people. Globally, the prevalence of uninvestigated dyspepsia (UD) varies between 7%-45%, depending on definition used and geographical location, whilst the prevalence of FD has been noted to vary between 11%-29.2%. Risk factors for FD have been shown to include females and underlying psychological disturbances, whilst environmental/ lifestyle habits such as poor socio-economic status, smoking, increased caffeine intake and ingestion of non-steroidal anti-inflammatory drugs appear to be more relevant to UD. It is clear that dyspepsia and FD in particular are common conditions globally, affecting most populations, regardless of location.
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                Author and article information

                Journal
                rgp
                Revista de Gastroenterología del Perú
                Rev. gastroenterol. Perú
                Sociedad de Gastroenterología del Perú (Lima, , Peru )
                1022-5129
                July 2015
                : 35
                : 3
                : 219-225
                Affiliations
                [02] Lima orgnameUniversidad Peruana de Ciencias Aplicadas orgdiv1Sociedad Científica de Estudiantes de Medicina Perú
                [01] Lima orgnameUniversidad Peruana de Ciencias Aplicadas orgdiv1Escuela de Medicina Perú
                [03] Lima orgnameEssalud orgdiv1Hospital Guillermo Kaelin de la Fuente Perú
                Article
                S1022-51292015000300002 S1022-5129(15)03500300002
                c303c2e7-23d7-4c52-a146-f576da371fec

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 27 November 2014
                : 19 May 2015
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 50, Pages: 7
                Product

                SciELO Peru

                Self URI: Texto completo solamente en formato PDF (ES)
                Categories
                Artículos originales

                Prevalence,Dispepsia,Síndrome de intestino irritable,Gastrointestinal diseases,Dolor abdominal,Prevalencia,Enfermedades gastrointestinales,Dyspepsia,Irritable bowel syndrome,Abdominal pain

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