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      Steroidal glycosides from the roots of Cynanchum amplexicaule Sieb. et Zucc.

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          Abstract

          Seven new steroidal glycosides (amplexicosides A (4), B (7), C (8), D (9), E (10), F (11), and G (12)), along with six known compounds (cynatratoside A (1), tylophoside A (2), cynatratoside B (3), glaucogenin A (5), glaucoside A (6), and hancoside A (13)) were isolated from the 95% ethanol extract of the roots of Cynanchum amplexicaule (Sieb. et Zucc.). Their structures were determined based on spectral and chemical evidence. Compound 12 has a 14, 15-secopregnane-type skeleton aglycone, which has not been reported in literature.

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          Author and article information

          Journal
          Steroids
          Steroids
          Elsevier BV
          0039-128X
          0039-128X
          Jul 2008
          : 73
          : 6
          Affiliations
          [1 ] School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, No. 103 Wenhua Road, Shenyang 110016, People's Republic of China.
          Article
          S0039-128X(08)00051-2
          10.1016/j.steroids.2008.01.024
          18343471
          c371bdc0-a2cd-4a64-9382-5334448dc3f4
          History

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