A Case of IgA Nephropathy Associated with Adeno- and Herpes Simplex Viruses

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Abstract

We report here an adult case of IgA nephropathy associated with episodes of recurrent tonsillitis. Various kinds of viral antigens were examined in the renal and tonsillar tissues by immunofluorescence. Granular depositions of adeno- and herpes simplex viral antigens were detected in the glomerular mesangial areas and in the tonsillar epithelial cells by immunofluorescence. IgA and IgAl deposits were also observed in the glomerular mesangial areas. It was suggested that IgA nephropathy might be caused by multiple antigenic substances, including adeno- and/or herpes simplex viruses, located in the tonsillar regions.

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Journal

Journal ID (publisher-id): NEF

Journal ID (nlm-ta): Nephron

Journal ID (doi): 10.1159/issn.1660-8151

Title: Nephron

Publisher: S. Karger AG

ISSN (Print): 1660-8151

ISSN (Electronic): 2235-3186

Publication date Subscription-year: 1987

Publication date (Print): 1987

Publication date (Electronic): 05 December 2008

Volume: 47

Issue: 4

Pages: 258-261

Affiliations

Department of Internal Medicine, School of Medicine, Tokai University, Isehara City, Kanagawa-Ken, Japan

Article

Publisher ID: 184520 Other ID: Nephron 1987;47:258–261

DOI: 10.1159/000184520

PubMed ID: 2827043

SO-VID: c413a5eb-eccf-440d-88d8-e9bd82409046

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date accepted : 20 February 1987

Page count

Pages: 4

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