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Short-interval and long-interval intracortical inhibition of TMS-evoked EEG potentials
Isabella Premoli ,
Julia Király ,
Florian Müller-Dahlhaus ,
Carl M. Zipser ,
Pierre Rossini ,
Christoph Zrenner ,
Ulf Ziemann ,
Paolo Belardinelli
July 2018
July 2018
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Abstract
Inhibition in the human motor cortex can be probed by means of paired-pulse transcranial
magnetic stimulation (ppTMS) at interstimulus intervals of 2-3 ms (short-interval
intracortical inhibition, SICI) or ∼100 ms (long-interval intracortical inhibition,
LICI). Conventionally, SICI and LICI are recorded as motor evoked potential (MEP)
inhibition in the hand muscle. Pharmacological experiments indicate that they are
mediated by GABAA and GABAB receptors, respectively.