8
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Outcomes of Single Segment Implantation of Conventional Intacs versus Intacs SK for Keratoconus

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Purpose:

          To compare the visual, refractive, and keratometric outcomes of single-segment conventional and severe keratoconus (SK) types of Intacs for correction of inferior keratoconus (KCN).

          Methods:

          A total number of 41 consecutive eyes of 23 patients with a diagnosis of inferior KCN underwent Intacs implantation. Eight eyes were excluded due to postoperative complications (4 eyes) and loss to follow-up (4 eyes) and finally 33 eyes underwent statistical analysis. Two groups were created according to Intacs type insertion; conventional group (17 eyes) and SK groups (16 eyes). Intracorneal ring segments (ICRS) implantation was indicated in keratoconic patients with contact-lens intolerance or reduced best spectacle-corrected visual acuity (BSCVA).

          Results:

          In the conventional group, mean uncorrected distance visual acuity (UCDVA) improved from 0.45 ± 0.41 preoperatively to 0.69 ± 0.39 six months after surgery representing a gain of 2 Snellen lines, and in the SK group mean UCDVA changed from 0.40 ± 0.35 preoperatively to 0.58 ± 0.48 equivalent to two Snellen lines improvement 6 months after operation ( P = 0.48). Mean preoperative BSCVA in the conventional group improved from 0.72 ± 0.41 to 0.86 ± 0.39 (2 lines improvement) postoperatively and in the SK group improved from 0.71 ± 0.69 to 0.75 ± 0.45 (0.50 line improvement) ( P = 0.29). Mean preoperative spherical equivalent (SE) decreased from −4.86 ± 2.26 D to −3.57 ± 2.21 D (conventional group) and from −4.20 ± 1.82 D to −3.60 ± 1.89 D ( P = 0.34), mean astigmatism (AST) decreased from −5.20 ± 2.07 D and −4.50 ± 2.26 D to −4.02 ± 2.57 D and − 3.18 ± 2.14 D in the conventional and SK groups, respectively ( P = 0.68). Finally, mean K min decreased from 47.11 ± 2.51 D to 45.40 ± 3.30 D in the conventional group and from 45.05 ± 2.59 D to 44 ± 3.88 D in the SK group ( P = 0.63) and mean K max was decreased from 52.82 ± 3.23 D to 50.52 ± 3.57 D and from 49.72 ± 3.17 D to 48.55 ± 4.50 D, respectively ( P = 0.48).

          Conclusion:

          Single-segment implantation of conventional and SK Intacs improved UCDVA and BSCVA, decreased corneal AST and keratometry in both groups with comparable outcomes.

          Related collections

          Most cited references18

          • Record: found
          • Abstract: found
          • Article: not found

          Correcting keratoconus with intracorneal rings.

          To evaluate the potential of intrastromal corneal ring technology (Intacs, KeraVision) to correct keratoconus without central corneal scarring. Department of Ophthalmology, Brest University Hospital, Brest, France. In this prospective, noncomparative, interventional case series, Intacs segments were implanted in 10 keratoconic eyes with clear central corneas and contact lens intolerance after corneal pachymetry was checked. Segment thicknesses varied based on corneal topography analysis. No intraoperative complications occurred. The mean follow-up was 10.6 months. Postoperative results revealed a reduction in astigmatism and spherical correction and an increase in topographical regularity and increased uncorrected visual acuity. Intacs technology can reduce the corneal steepening and astigmatism associated with keratoconus.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Effect of inferior-segment Intacs with and without C3-R on keratoconus.

            To determine whether corneal collagen cross-linking with riboflavin (C3-R) augments the effect of inferior-segment Intacs (Addition Technology) in the treatment of keratoconus. Private practice, Beverly Hills, California, USA. A retrospective nonrandomized comparative case series comprised 12 eyes of 9 patients who had inferior-segment Intacs placement without C3-R (Intacs-only group) and 13 eyes of 12 patients who had inferior-segment Intacs placement combined with C3-R (Intacs with C3-R group). The 2 groups were matched preoperatively. All patients had inferior-segment Intacs placed with the incision in the steep axis of manifest refraction. Corneal collagen cross-linking with riboflavin was performed after the Intacs segments were inserted. Outcome measures were topographic keratometry values and the lower-upper (L-U) ratio, which is a topographic measure of the degree of keratoconus. Preoperative data were compared to results 1 day postoperatively and measurements at the last postoperative visit. The Intacs with C3-R group had a significantly greater reduction in cylinder than the Intacs-only group (P<.05). Steep and average keratometry were reduced significantly more in the Intacs with C3-R group (P<.05). There was a greater reduction in L-U ratio in the Intacs with C3-R group (P<.05). The addition of C3-R to the Intacs procedure resulted in greater keratoconus improvements than Intacs insertion alone.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Refractive and aberrometric outcomes of intracorneal ring segments for keratoconus: mechanical versus femtosecond-assisted procedures.

              To compare visual, refractive, and corneal aberrometric outcomes in keratoconic eyes implanted with intracorneal ring segments (ICRS) implantation using either a mechanical or a femtosecond laser-assisted procedure. Retrospective, consecutive case series. A total of 146 consecutive eyes of 106 patients with the diagnosis of keratoconus (68 unilateral and 39 bilateral) were included. Two groups were created according to the surgical technique used for corneal tunnelization: Mechanical group (mechanical tunnelization, 63 eyes) and Femtosecond group (femtosecond laser-assisted tunnelization, 83 eyes). Intracorneal ring segments implantation was indicated because of the existence of reduced best spectacle-corrected visual acuity (BSCVA) or contact lens intolerance. Intracorneal ring segments implantations were performed by 6 surgeons following the same protocol except for the incision location. A total of 55 eyes were implanted with Intacs (Addition Technology, Inc, Fremont, CA) and 8 eyes were implanted with KeraRings (Mediphacos, Belo Horizonte, Brazil) in the Mechanical group, and 25 eyes were implanted with Intacs and 58 eyes were implanted with KeraRings in the Femtosecond group. Mean follow-up was 10.66+/-8.20 months, ranging from 1 month to 24 months. Uncorrected visual acuity (UCVA), BSCVA, refraction, keratometry, and root mean square (RMS) for different kinds of corneal aberrations. By reporting only for statistically significant changes, UCVA improved in both groups at 6 months (P 0.63, P< or =0.04). Intracorneal ring segments implantation using both mechanical and femtosecond laser-assisted procedures provide similar visual and refractive outcomes. A more limited aberrometric correction is observed for eyes with mechanical implantation. The author(s) have no proprietary or commercial interest in any materials discussed in this article.
                Bookmark

                Author and article information

                Journal
                J Ophthalmic Vis Res
                J Ophthalmic Vis Res
                JOVR
                Journal of Ophthalmic & Vision Research
                Medknow Publications & Media Pvt Ltd (India )
                2008-2010
                2008-322X
                Jul-Sep 2014
                : 9
                : 3
                : 305-309
                Affiliations
                [1] Cornea Department, Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
                Author notes
                Correspondence to: Mehrdad Mohammadpour. Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran. E-mail: mahammadpour@ 123456yahoo.com
                Article
                JOVR-9-305
                10.4103/2008-322X.143359
                4307661
                c48ab717-2ccb-4efd-a702-1bd3c32adada
                Copyright: © Journal of Ophthalmic and Vision Research

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 23 October 2013
                : 15 February 2014
                Categories
                Original Article

                Ophthalmology & Optometry
                intacs,keratoconus,single-segment
                Ophthalmology & Optometry
                intacs, keratoconus, single-segment

                Comments

                Comment on this article