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      Diagnostic tools in ocular allergy

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          Methodologies to diagnose and monitor dry eye disease: report of the Diagnostic Methodology Subcommittee of the International Dry Eye WorkShop (2007).

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          The role of the Diagnostic Methodology Subcommittee of the Dry Eye Workshop was 1) to identify tests used to screen, diagnose and monitor dry eye disease, 2) to establish criteria for test performance, and 3) to consider the utility of tests in a variety of clinical settings. The committee created a database of tests used to diagnose and monitor dry eye, each compiled by an expert in the field (rapporteur) and presented within a standard template. Development of the templates involved an iterative process between the Chairman of the subcommittee, the rapporteurs, and, at times, an additional group of expert reviewers. This process is ongoing. Each rapporteur was instructed on how to the complete a template, using a proforma template and an example of a completed template. Rapporteurs used the literature and other available sources as the basis for constructing their assigned template. The chairman of the subcommittee modifed the template to produce a standardized version and reviewed it with the rapporteur. The completed database will be searchable by an alphabetical list of test names, as well as by functional groupings, for instance, tests of aqueous dynamics, lipid functions, etc. The templates can be accessed on the website of the Tear Film and Ocular Surface Society (www.tearfilm.org). This report provides a general overview of the criteria applied in the development of tests for screening and diagnosis.
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            Practical guide to skin prick tests in allergy to aeroallergens.

            This pocket guide is the result of a consensus reached between members of the Global Allergy and Asthma European Network (GA(2) LEN) and Allergic Rhinitis and its Impact on Asthma (ARIA). The aim of the current pocket guide is to offer a comprehensive set of recommendations on the use of skin prick tests in allergic rhinitis-conjunctivitis and asthma in daily practice. This pocket guide is meant to give simple answers to the most frequent questions raised by practitioners in Europe, including 'practicing allergists', general practitioners and any other physicians with special interest in the management of allergic diseases. It is not a long or detailed scientific review of the topic. However, the recommendations in this pocket guide were compiled following an in-depth review of existing guidelines and publications, including the 1993 European Academy of Allergy and Clinical Immunology position paper, the 2001 ARIA document and the ARIA update 2008 (prepared in collaboration with GA(2) LEN). The recommendations cover skin test methodology and interpretation, allergen extracts to be used, as well as indications in a variety of settings including paediatrics and developing countries. © 2011 John Wiley & Sons A/S.
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              Recommendations for standardization of clinical trials with Allergen Specific Immunotherapy for respiratory allergy. A statement of a World Allergy Organization (WAO) taskforce.

              Specific Immunotherapy for respiratory allergy is used since about one century and there is now solid documentation of its efficacy. Nevertheless, the methods and experimental designs used in clinical trials are quite heterogeneous and there is no unanimously accepted methodological standard. Many studies are planned with study designs that may not confirm the clinical value of SIT as an effective treatment to reduce disease severity. To ensure that patients are treated based on sound scientific evidence and to minimize the risk of misusing limited financial resources for scientific studies, the World Allergy Organization (WAO) convened a group of experts to provide guidelines for the methodology of future immunotherapy studies. This document summarizes the recommendations for study design, patients' selection, appropriate outcomes and statistical treatment to be used in planning and performing clinical trials with specific immunotherapy.
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                Author and article information

                Journal
                Allergy
                Allergy
                Wiley
                01054538
                October 2017
                October 2017
                May 10 2017
                : 72
                : 10
                : 1485-1498
                Affiliations
                [1 ]Department of Neuroscience; Ophthalmology Unit; University of Padua; Padua Italy
                [2 ]Service d'Ophtalmologie; Hôpital Bichat and Fondation A. de Rothschild; Paris France
                [3 ]Unité d'Allergologie de l'Enfant CHU Estaing; CHU Estaing; Clermont-Ferrand Cedex1 France
                [4 ]Faculty of Medicine; Department of Ophthalmology; Selcuk University; Konya Turkey
                [5 ]Rapallo Hospital Ophthalmology Department; Allergic Conjunctivitis Unit; Ocular Inflammatory Diseases Referral Center; Genova Italy
                [6 ]Pole sanitaire du Vexin; Pontoise France
                [7 ]Allergy Unit; Regional University Hospital of Malaga; IBIMA, UMA; Malaga Spain
                [8 ]Department of Immunology, Rheumatology and Allergy; Medical University of Lodz; Lodz Poland
                [9 ]University Hospitals Leuven; Leuven Belgium
                [10 ]Laboratory of Immunology; Faculty of Medicine; Basic and Clinical Immunology Unit, and Center for Research in Health Technologies and Information Systems (CINTESIS); University of Porto; Porto Portugal
                [11 ]Department of Ocular Biology & Therapeutics; UCL Institute of Ophthalmology; London UK
                Article
                10.1111/all.13178
                28387947
                c498fcc9-1f27-4b88-935d-b8ff46b544a3
                © 2017

                http://doi.wiley.com/10.1002/tdm_license_1.1

                http://onlinelibrary.wiley.com/termsAndConditions#vor

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