Outcome of Low Birthweight

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Abstract

Babies who are small at birth and during infancy are now known to be at an increased risk of developing coronary heart disease, hypertension and diabetes during adult life. This has led to the suggestion that these diseases are ‘programmed’ by an inadequate supply of nutrients or oxygen in utero or immediately after birth. The phenomenon of ‘programming’, whereby undernutrition in early life permanently changes body structure and function, is well documented in animals. As yet we know little about cellular and molecular changes which underlie it, but persisting changes in the secretion of hormones or in the sensitivity of tissues to them may be important in determining adult disease.

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Journal

Journal ID (publisher-id): HRE

Journal ID (nlm-ta): Horm Res Paediatr

Journal ID (doi): 10.1159/issn.1663-2818

Title: Hormone Research in Paediatrics

Publisher: S. Karger AG

ISBN: 978-3-8055-6093-1

ISBN: 978-3-318-01591-1

ISSN (Print): 1663-2818

ISSN (Electronic): 1663-2826

Publication date Subscription-year: 1994

Publication date (Print): 1994

Publication date (Electronic): 05 December 2008

Volume: 42

Issue: 4-5

Pages: 223-230

Affiliations

Medical Research Council Environmental Epidemiology Unit, University of Southampton, UK

Article

Publisher ID: 184197 Other ID: Horm Res 1994;42:223–230

DOI: 10.1159/000184197

PubMed ID: 7868077

SO-VID: c5173310-9de2-44ae-98ff-a8c882bbd213

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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Pages: 8

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