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      Perioperative Coagulation Management in Liver Transplant Recipients.

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          Abstract

          We review contemporary coagulation management for patients undergoing liver transplantation. A better understanding of the complex physiologic changes that occur in patients with end-stage liver disease has resulted in significant advances in anesthetic and coagulation management. A group of internationally recognized experts have critically evaluated current approaches for coagulopathy detection and management. Strategies for blood component and factor replacement have been evaluated and recommended therapies proposed. Pharmacologic treatment and prevention of coagulopathy, management of patients receiving antiplatelet medications, and the role of transesophageal echocardiography for early detection and management of thromboses are presented.

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          Author and article information

          Journal
          Transplantation
          Transplantation
          Ovid Technologies (Wolters Kluwer Health)
          1534-6080
          0041-1337
          April 2018
          : 102
          : 4
          Affiliations
          [1 ] Department of Anesthesia and Perioperative Medicine, Penn State University, Penn State College of Medicine, Hershey, PA.
          [2 ] Department of Anesthesiology and Intensive Care, University Hospital Essen, Essen, Germany.
          [3 ] Department of Anesthesia and Perioperative Medicine, Mayo Clinic, Rochester, MN.
          [4 ] Department of Anesthesiology, Cleveland Clinic, Jacksonville, FL.
          [5 ] Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami, Miami, FL.
          [6 ] Department of Anesthesiology, Cairo University, Cairo, Egypt.
          [7 ] Department of Anesthesiology Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY.
          [8 ] Department of Anesthesiology, University of Texas, Houston, TX.
          [9 ] Department of Anesthesiology, Mayo Clinic, Phoenix, AZ.
          [10 ] Department of General, Visceral and Transplant Surgery, University Hospital Essen, Essen, Germany.
          [11 ] Department of Anesthesiology, UCLA Medical Center, Los-Angeles, CA.
          [12 ] Department of Anesthesiology, Columbia University, New York, NY.
          [13 ] Department of Anesthesiology, University of Tennessee, Memphis, TN.
          Article
          10.1097/TP.0000000000002092
          29337842
          c51b8ec5-cdc1-4761-b701-de814225f7dc
          History

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