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Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma : A Randomized Clinical Trial
Roger Stupp ,
Sophie Taillibert ,
Andrew Kanner ,
William Read ,
David M. Steinberg ,
Benoit Lhermitte ,
Steven Toms ,
Ahmed Idbaih ,
Manmeet S. Ahluwalia ,
Karen Fink ,
Francesco Di Meco ,
Frank Lieberman ,
Jay-Jiguang Zhu ,
Giuseppe Stragliotto ,
David D. Tran ,
Steven Brem ,
Andreas F. Hottinger ,
Eilon D. Kirson ,
Gitit Lavy-Shahaf ,
Uri Weinberg ,
Chae-Yong Kim ,
Sun-Ha Paek ,
Garth Nicholas ,
Jordi Burna ,
Hal Hirte ,
Michael Weller ,
Yoram Palti ,
Monika E. Hegi ,
Zvi Ram
December 19 2017
December 19 2017
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Abstract
Tumor-treating fields (TTFields) is an antimitotic treatment modality that interferes
with glioblastoma cell division and organelle assembly by delivering low-intensity
alternating electric fields to the tumor.