9
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Colonización por ESKAPES y características clínicas de pacientes en estado crítico Translated title: Colonization by ESKAPES and clinical characteristics of critically ill patients Translated title: Colonização por ESKAPES e características clínicas de pacientes críticos

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          RESUMEN: Objetivo: Identificar la colonización por ESKAPES y las características clínicas de los pacientes hospitalizados en una Unidad de Cuidados Intensivos para Adultos de un hospital mixto en Paraná. Método: Investigación de campo, descriptiva, documental y experimental con enfoque cuantitativo, desarollada en una Unidad de Cuidados Intensivos adultos de un hospital mixto en el suroeste de Paraná, Brasil. La población del estudio consistió en pacientes con ingreso de 48 horas en la Unidad de Cuidados Intensivos, de abril a agosto de 2018 y de abril a agosto de 2019. La muestra totalizó 102 individuos. Para la recopilación de datos clínicos, se utilizó un Checklist y para el análisis microbiológico se recogieron muestras de las cavidades nasales y orales y la secreción traqueal. El análisis de los datos clínicos se produjo a través del software Statistical Package for the Social Sciences. Se realizaron pruebas de frecuencia y chi-cuadrado, teniendo en cuenta la p<0,05 significativa. Resultados: Se evaluaron un total de 102 pacientes ingresados en la Unidad de Cuidados Intensivos durante el período estudiado. De ellos, 57 (55,8%) fueron colonizados por microorganismos patógenos. En cuanto a la colonización por microorganismos, predominan Staphylococcus aureus (61,4%), seguido de Klebsiella pneumoniae (40,4%), Pseudomonas aeruginosa (26,3%) y Staphylococcus epidermidis (21,1%). Cabe destacar que Klebsiella pneumoniae y Staphylococcus aureus estuvieron presentes en las tres regiones evaluadas. Conclusión: El estudio identificó la presencia de colonización en pacientes en estado crítico estudiados, siendo esta colonización, en su mayoría, por bacterias resistentes pertenecientes al grupo ESKAPE.

          Translated abstract

          ABSTRACT: Objective: To identify colonization by ESKAPES and clinical characteristics of patients admitted in Adult Intensive Care Unit of a mixed hospital in Paraná. Method: Field research, descriptive, documentary and experimental quantitative approach, developed in adult Intensive Care Unit of a mixed hospital in Southwest Paraná, Brazil. The study population consisted of patients with admission from 48 hours in the Intensive Care Unit, from April to August 2018 and April to August 2019. The sample has 102 individuals. For the collection of clinical data, a checklist was used and for microbiological analysis the sample was collected from nasal and oral cavities and tracheal secretion. The analysis of clinical data occurred through the Statistical Package for the Social Sciences software. Descriptive frequency and chi-square test, considering significant p <0,05. Results: A total of 102 patients admitted to the Intensive Care Unit during the period studied were evaluated. On these ones, 57 (55,8%) were colonized by pathogenic microorganisms. Regarding the colonization of microorganisms, there was predominance of Staphylococcus aureus (61,4%), followed by Klebsiella pneumoniae (40,4%), Pseudomonas aeruginosa (26,3%) and Staphylococcus epidermidis (21,1%). It is noteworthy that Klebsiella pneumoniae and Staphylococcus aureus were present in the three regions evaluated. Conclusion: The study identified the presence of colonization in critically ill patients studied, being this colonization, mostly, resistant bacteria belonging to the ESKAPE group.

          Translated abstract

          RESUMO: Objetivo Identificar a colonização por ESKAPES e características clínicas de pacientes internados em uma Unidade de Terapia Intensiva Adulto de um hospital misto do Paraná. Método Pesquisa de campo, descritiva, documental e experimental com abordagem quantitativa, desenvolvida em uma Unidade de Terapia Intensiva adulto de um hospital misto do Sudoeste do Paraná, Brasil. A população do estudo constituiu-se pelos pacientes com admissão a partir de 48 horas na Unidade de Terapia Intensiva, no período de abril a agosto de 2018 e de abril a agosto de 2019. A amostra totalizou 102 indivíduos. Para a coleta de dados clínicos foi utilizado um Checklist e para a análise microbiológica foram coletadas amostras das cavidades nasal e oral e secreção traqueal. A análise dos dados ocorreu por meio do software Statistical Package for the Social Sciences. Realizou-se frequência descritiva e teste de qui-quadrado, considerando significativo p <0,05. Resultados: Foram avaliados 102 pacientes admitidos na Unidade de Terapia Intensiva durante o período pesquisado. Destes, 57 (55,8%) estavam colonizados por microrganismos patogênicos. Em relação à colonização de microrganismos, houve predominância de Staphylococcus aureus (61,4%), seguido por Klebsiella pneumoniae (40,4%), Pseudomonas aeruginosa (26,3%) e Staphylococcus epidermidis (21,1%). Vale ressaltar que, Klebsiella pneumoniae e Staphylococcus aureus estiveram presentes nas três regiões avaliadas. Conclusão O estudo identificou a presença de colonização nos pacientes criticamente enfermos pesquisados, sendo essa colonização, em sua maioria, por bactérias resistentes pertencentes ao grupo ESKAPE.

          Related collections

          Most cited references25

          • Record: found
          • Abstract: not found
          • Book: not found

          Tackling drug‐resistant infections globally: final report and recommendations

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            A Prospective Cohort Multicenter Study of Molecular Epidemiology and Phylogenomics of Staphylococcus aureus Bacteremia in Nine Latin American Countries.

            Staphylococcus aureus is an important pathogen causing a spectrum of diseases ranging from mild skin and soft tissue infections to life-threatening conditions. Bloodstream infections are particularly important, and the treatment approach is complicated by the presence of methicillin-resistantS. aureus(MRSA) isolates. The emergence of new genetic lineages of MRSA has occurred in Latin America (LA) with the rise and dissemination of the community-associated USA300 Latin American variant (USA300-LV). Here, we prospectively characterized bloodstream MRSA recovered from selected hospitals in 9 Latin American countries. All isolates were typed by pulsed-field gel electrophoresis (PFGE) and subjected to antibiotic susceptibility testing. Whole-genome sequencing was performed on 96 MRSA representatives. MRSA represented 45% of all (1,185S. aureus) isolates. The majority of MRSA isolates belonged to clonal cluster (CC) 5. In Colombia and Ecuador, most isolates (≥72%) belonged to the USA300-LV lineage (CC8). Phylogenetic reconstructions indicated that MRSA isolates from participating hospitals belonged to three major clades. Clade A grouped isolates with sequence type 5 (ST5), ST105, and ST1011 (mostly staphylococcal chromosomal cassettemec[SCCmec] I and II). Clade B included ST8, ST88, ST97, and ST72 strains (SCCmecIV, subtypes a, b, and c/E), and clade C grouped mostly Argentinian MRSA belonging to ST30. In summary, CC5 MRSA was prevalent in bloodstream infections in LA with the exception of Colombia and Ecuador, where USA300-LV is now the dominant lineage. Clonal replacement appears to be a common phenomenon, and continuous surveillance is crucial to identify changes in the molecular epidemiology of MRSA.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              Clinical characteristics, antimicrobial resistance and capsular types of community-acquired, healthcare-associated, and nosocomial Klebsiella pneumoniae bacteremia

              Background Klebsiella pneumoniae bacteremia is a major cause of morbidity and mortality worldwide. We aimed to compare the clinical characteristics, distribution of capsular types, and antimicrobial resistance of K. pneumoniae bacteremia among community-acquired (CA), healthcare-associated (HCA), and nosocomial infections. Methods This retrospective study of patients with K. pneumoniae bacteremia was conducted at Taipei Veterans General Hospital from January to December 2015. Clinical characteristics of K. pneumoniae bacteremia were collected. The K. pneumoniae isolates were subjected to antimicrobial susceptibility testing and capsular genotyping. Results In total, 337 patients with K. pneumoniae bacteremia were identified: 70 (20.8%), 102 (30.3%), and 165 (48.9%) presented with CA, HCA, and nosocomial infection, respectively. The 28-day mortality of HCA bacteremia was lower than that of nosocomial bacteremia (17.6% versus 30.9%, p = 0.016); however, that of the HCA and CA bacteremia was similar (17.6% versus 14.3%, p = 0.557). CA isolates had the highest prevalence of virulent capsular types (51.4%), followed by HCA (36.3%) and nosocomial isolates (19.4%). The proportion of multidrug-resistant (MDR) isolates was highest in nosocomial infections (41.8%), followed by HCA (23.5%) and CA infections (5.7%). Conclusion CA, HCA and nosocomial K. pneumoniae are distinct entities, as evidenced by the differences in clinical characteristics, antimicrobial resistance, and capsular types found in this study.
                Bookmark

                Author and article information

                Journal
                eg
                Enfermería Global
                Enferm. glob.
                Universidad de Murcia (Murcia, Murcia, Spain )
                1695-6141
                2020
                : 19
                : 59
                : 214-254
                Affiliations
                [2] orgnameUniversidad Paranaense - Unipar Brasil
                [3] orgnameUniversidad Paranaense - Unipar Brasil
                [4] orgnameUniversidad Paranaense - Unipar Brasil
                [5] orgnameUniversidad Paranaense Brasil
                [1] orgnameUniversidad Paranaense - Unipar Brasil franciele.ns@ 123456prof.unipar.br
                Article
                S1695-61412020000300214 S1695-6141(20)01905900214
                10.6018/eglobal.406691
                c56a049a-a174-4e7e-8748-fc30f9a35839

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 International License.

                History
                : 17 February 2020
                : 13 December 2019
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 29, Pages: 41
                Product

                SciELO Spain

                Categories
                Originales

                Unidades de Cuidados Intensivos,Intensive Care Units,Infection,Drug Resistance Microbial,Bacteria,Infecção,Resistência Microbiana a medicamentos,Bactérias,Unidades de Terapia Intensiva,infección,resistencia microbiana a medicamentos,bacterias

                Comments

                Comment on this article