Aethiopomyia Malloch ( Diptera , Muscidae ) is a small genus with occurrence restricted to the Afrotropical region. Only five species are currently known in this genus: A. patersoni Zumpt, 1969, A. williamsi Snyder, 1951, A. arguta (Karsch, 1879), A. steini Curran, 1935, and A. gigas (Stein, 1906). All Aethiopomyia species are large, reaching up to 15 mm, as in A. patersoni and the most visible differences among them are based in the color pattern of the body. The species are mostly yellow, with a broad scutum and abdomen, males and females are dichoptic, the anepimeron is haired and they have stubby spines on the upper side of the palpi. Phylogenetically, Aethiopomyia , together with two other genera restricted to the Afrotropical region, Alluaudinella Giglio-Tos and Ochromusca Malloch, appear to form a monophyletic group, defined by the presence of the remarkably short stubby spines on the upper side of the palpi. Four species deposited in the Museum für Naturkunde, Berlin (Germany) were analyzed; three of them are types. Diagnosis for all species, colored illustrations, male dissections and illustrations and a key to separate them are presented herein.