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      Outcome of Treatment of Anterior Vaginal Wall Prolapse and Stress Urinary Incontinence with Transobturator Tension-Free Vaginal Mesh (Prolift) and Concomitant Tension-Free Vaginal Tape-Obturator

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          Abstract

          Objective. It is to assess the feasibility, effectiveness, and safety of transobturator tension-free vaginal mesh (Prolift) and concomitant tension-free vaginal tape-obturator (TVT-O) system as a treatment of female anterior vaginal wall prolapse associated with stress urinary incontinence (SUI). Patients and Methods. Between December 2006 and July 2007, 20 patients with anterior genital prolapse and voiding dysfunction were treated with the transobturator tension-free vaginal mesh (Prolift) and concomitant tension-free vaginal tape-obturator (TVT-O). Sixteen patients had stress urinary incontinence and 4 patients were considered at risk for development of de novo stress incontinence after the prolapse is repaired. All patients underwent a complete urodynamic assessment. All the patients underwent pelvic examination 4–6 weeks after the operation, and anatomical and functional outcomes were recorded. Results. Twenty cystocoeles were repaired: 6 grade II, 12 grade III, and 2 grade IV. There were no vessel or bladder injuries. Eighteen patients had optimal anatomic results and 2 patients had persistent asymptomatic stage I prolapse. Conclusion. These preliminary results suggest that Prolift system offers a safe and effective treatment for female anterior vaginal wall prolapse. However, a long-term followup is necessary in order to support the good result maintenance.

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          Most cited references31

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          Risk factors for prolapse recurrence after vaginal repair.

          The purpose of this study was to determine factors that are associated with recurrent prolapse. Of 389 women who underwent vaginal prolapse and incontinence between June 1996 and May 1999, 176 women had 1-year follow-up evaluations. Recurrent prolapse was analyzed by both pelvic organ prolapse quantification stage and centimeter measurements that were relative to the hymen. Logistic regression was used to determine odds ratios and 95% CI for factors that were associated with recurrent prolapse. One year after surgery, 102 women (58%) had recurrent prolapse (>/=stage II). Seventeen women (10%) had prolapse >/=1 cm beyond the hymen. Age /=stage II) at 1 year. Younger women and women with more advanced prolapse are more likely to experience recurrent prolapse after vaginal repair.
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            Anatomy and biomechanics of genital prolapse.

            J DeLancey (1993)
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              The efficacy of Marlex mesh in the repair of severe, recurrent vaginal prolapse of the anterior midvaginal wall.

              The study assesses the efficacy and complications of Marlex mesh in repairing severe recurrent anterior vaginal wall prolapse. Twenty-four patients with two or more postsurgical recurrences of severe anterior vaginal wall prolapse were divided into control and treatment groups. Transvaginal repair was similar between groups except for reinforcement of the anterior vaginal wall with synthetic mesh. Two examiners graded preoperative and postoperative support over the following 2 years (K = 0.9). Fisher's exact test, log-linear analysis, and analysis of variance were used to compare categoric and continuous variables. Four patients in the control group and none in the treatment group had recurrent anterior vaginal wall prolapse (p < 0.05). Three patients had mesh-related complications. Repair with a synthetic mesh decreased the expected incidence of severe recurrent anterior vaginal prolapse but was associated with common complications related to synthetic mesh. Mesh reinforcement is an effective treatment for severe recurrent prolapse of the anterior midvaginal wall.
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                Author and article information

                Journal
                Adv Urol
                AU
                Advances in Urology
                Hindawi Publishing Corporation
                1687-6369
                1687-6377
                2009
                25 December 2008
                : 2009
                : 341268
                Affiliations
                1Department of Urology, Cairo University, Cairo, Egypt
                2Department of Gynaecology, October 6 University, October 6 City, Egypt
                3Department of Gynaecology, Well-Care Medical Centre, Abudhabi, United Arab Emirates
                Author notes

                Recommended by Flavio Trigo Rocha

                Article
                10.1155/2009/341268
                2610388
                19125198
                c63be87f-7d25-49b9-8c84-7c3b0683c946
                Copyright © 2009 Ashraf Abou-Elela et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 4 August 2008
                : 18 September 2008
                : 17 October 2008
                Categories
                Clinical Study

                Urology
                Urology

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