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      Instant to Instant Reflex Cardiac Regulation

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          Abstract

          The mechanical activation of localized regions of the vena cava, atria, ventricles, or thoracic aorta reflexly initiate preganglionic and postganglionic efferent sympathetic traffic in cardiac nerves. This traffic responds to altered cardio-dynamics. On the other hand, efferent vagal traffic in cardiac nerves is directly modified only by carotid and pulmonary artery mechanics. Afferent stimulation of cardiac nerves elicits reflex activation of preganglionic and postganglionic cardiac sympathetic efferents from 20 to 300 msec after the stimulus. These cardio-cardiac reflexes involve afferents travelling via the sympathetics or vagi. The modulation of cardiac parasympathetic or sympathetic efferent traffic throughout each cardiac cycle indicates not only the highly localized nature of the cardio-cardiac and vascular-cardiac reflexes, but also their rapid adaptability, and the presence of positive as well as negative feedback mechanisms.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1976
          1976
          29 October 2008
          : 61
          : 5-6
          : 309-328
          Affiliations
          Department of Physiology, Loyola University, Stritch School of Medicine, Maywood, Ill.
          Article
          169778 Cardiology 1976;61:309–328
          10.1159/000169778
          © 1976 S. Karger AG, Basel

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          Page count
          Pages: 20
          Categories
          Original Paper

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