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      Acute postoperative biventricular failure associated with antiphospholipid antibody syndrome.

      BJA: British Journal of Anaesthesia

      therapy, Postoperative Complications, Plasmapheresis, methods, Perioperative Care, surgery, Mitral Valve Insufficiency, Humans, Heart Valve Prosthesis Implantation, Heart Failure, Female, Extracorporeal Membrane Oxygenation, Antiphospholipid Syndrome, Adult

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          Abstract

          Antiphospholipid syndrome is probably the most common acquired hypercoagulable state, but information on perioperative management is sparse. Minor alterations in anticoagulant therapy, infection, or a surgical insult may trigger widespread thrombosis. The perioperative course of a 31-yr-old woman with primary anticardiolipin antiphospholipid antibody syndrome requiring a mitral valve replacement is described. Postoperatively, she developed acute global biventricular failure requiring extracorporeal membrane oxygenation support and plasmapheresis. The management of anticoagulation and cardiac surgery in this condition is reviewed.

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          Journal
          10.1093/bja/aeh116
          15003982

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