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      Pharmacogenomics of neuropsychiatric disorders: analysis of genetic variability in 162 identified neuroreceptors using 1000 Genomes Project data.

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          Abstract

          Neuroreceptors are considered to be primary drug targets and their abrupt signaling is a notable cause of interindividual drug response variability and treatment failure for complex neuropsychiatric diseases. In view of recent evidence, it is believed that common genetic risk factors mainly highly polymorphic neuroreceptors are being shared among neuropsychiatric disorders.

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          Author and article information

          Journal
          Pharmacogenomics
          Pharmacogenomics
          Future Medicine Ltd
          1744-8042
          1462-2416
          2014
          : 15
          : 12
          Affiliations
          [1 ] Genomics & Molecular Medicine Unit, CSIR-Institute of Genomics & Integrative Biology, Mall Road, Delhi-110007, India.
          Article
          10.2217/pgs.14.113
          25340732
          c691b673-56ee-42ef-a314-2e9310c8c5be
          History

          population genetics,pharmacogenomics,neuroreceptors,drug discovery,genetic heterogeneity,neuropsychiatric disorders

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