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      Diode Laser Surgery of Recurrent White Lesion of the Lip: Clinicopathological Consideration and Cosmetic Outcome

      case-report
      1 , , 1 , 2
      ,
      Cureus
      Cureus
      diode laser, leukoplakia, oral surgery

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          Abstract

          Conventional surgery for potentially malignant lesions of the lip may result in unaesthetic sequela. Diode laser allows a careful surgical excision of lip lesions without intraoperative bleeding and stitches, promoting a fast mucosal healing, thereby leading to a complete restitutio ad integrum of lip mucosa without aesthetic complications.

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          Most cited references17

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          Malignant transformation of oral leukoplakia: a systematic review of observational studies.

          The aim of this systematic review was to ascertain the malignant transformation rate of oral leukoplakia and the associated risk factors.
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            Diode laser (808 nm) applied to oral soft tissue lesions: a retrospective study to assess histopathological diagnosis and evaluate physical damage.

            The diode laser is today widely used in oral pathology to excise lesions; however, some controversy surrounds laser surgery, specifically the accuracy of pathological diagnosis and the control over thermal tissue damage. This study aimed to establish if physical damage induced by the diode laser could affect the histopathological diagnosis and to evaluate the damage caused to the resection margins. Between 2005 and 2010, at S. Gerardo Hospital, Milan, 608 cases of soft tissue lesions localized in the oral cavity (cheek, gingiva, buccal mucosa, tongue, and lips) were examined. Specimens were excised with an 808-nm diode laser, output 1.6-2.7 W, in continuous-wave mode with fibers of 320 μm. Specimens were fixed in 10% buffered formalin solution and examined separately under an optical microscope by two pathologists. In all of the specimens, changes to the epithelium, connective tissue and blood vessels, shape of incision damage, and overall width of modified tissues were evaluated. The data for specimens larger than 3 mm excised with the diode laser were not significant in terms of stromal changes or vascular stasis, while epithelial and stromal changes were significantly more frequent in specimens with a mean size below 3 mm; the diagnosis was not achievable in 46.15%. Our data show that the diode laser is a valid therapeutic instrument for excising oral lesions larger than 3 mm in diameter, but induces serious thermal effects in small lesions (mean size below 3 mm). However, from a clinical standpoint, it is suggested necessary that the specimens taken have in vivo a diameter of at least 5 mm in order to have a reliable reading of the histological sample.
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              Prevalence and Risk Factors for Oral Potentially Malignant Disorders in Indian Population

              Objective. To assess the prevalence of oral potentially malignant disorders and to determine the potential risk factors for its development in Indian population. Materials and Methods. This cross-sectional study was carried out on 1241 individuals in Indore, Madhya Pradesh. A questionnaire was designed to record information about sociodemographic characteristics, oral hygiene practices, dietary habits, and risk factors for oral potentially malignant disorders. Oral mucosal lesions were examined by a skilled person. Results. The overall prevalence of oral potentially malignant disorders was found to be 13.7% with oral submucous fibrosis (8.06%) found to be more common and erythroplakia (0.24%) found to be least prevalent. Results of Logistic Regression analysis showed that males (OR = 2.09, P value < 0.0001) who were ever consumers of tobacco (OR = 2.06, P value = 0.030) and areca nut chewing (OR = 2.64, P value = 0.004) were more likely to develop oral potentially malignant disorders compared to never consumers. Diabetic (OR = 2.21, P value = 0.014) and underweight individuals (OR = 2.23, P value = 0.007) were more likely to suffer from oral potentially malignant disorders. Conclusion. The study reinforces the association of tobacco and areca nut consumption with oral potentially malignant disorders. An association of oral potentially malignant disorders with diabetes and BMI was confirmed by this study.
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                Author and article information

                Journal
                Cureus
                Cureus
                2168-8184
                Cureus
                Cureus (Palo Alto (CA) )
                2168-8184
                8 April 2020
                April 2020
                : 12
                : 4
                : e7585
                Affiliations
                [1 ] Dentistry, University of Bari Aldo Moro, Bari, ITA
                [2 ] Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, ITA
                Author notes
                Article
                10.7759/cureus.7585
                7212706
                c6a793fa-1422-4474-b570-aa7c12e99b6f
                Copyright © 2020, De Falco et al.

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 26 March 2020
                : 7 April 2020
                Categories
                Dentistry

                diode laser,leukoplakia,oral surgery
                diode laser, leukoplakia, oral surgery

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