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      • Record: found
      • Abstract: found
      • Article: found

      Rabbit Cornea Damage Induced by Alloxan

      research-article
      Author(s): , ,
      Publication date (Electronic):
      Journal: Ophthalmic Research
      Publisher: S. Karger AG
      Keywords: Alloxan damage, Corneal epithelium, Stromal oedema, Opacification, Vascularization

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          Abstract

          The application of alloxan solution to the rabbit cornea induces a profound damage to the stroma and endothelium of areas previously deprived of epithelium. A heavy oedema and opacification of the stroma appears in the course of the first day after application: later on, vascularization of the stroma occurs. All the steps of this process were followed experimentally by means of the silver staining methods of Jabonero and McGovern, routine histological staining, and supravital staining with methylene blue.

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          Author and article information

          Journal
          Journal ID (publisher-id): ORE
          Journal ID (nlm-ta): Ophthalmic Res
          Journal ID (doi): 10.1159/issn.0030-3747
          Title: Ophthalmic Research
          Publisher: S. Karger AG
          ISSN (Print): 0030-3747
          ISSN (Electronic): 1423-0259
          Publication date Subscription-year: 1976
          Publication date (Print): 1976
          Publication date (Electronic): 03 December 2009
          Volume: 8
          Issue: 4
          Pages: 262-275
          Affiliations
          Eye Clinic, Charles University, Prague, and Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, N.Y.
          Article
          Publisher ID: 264832 Other ID: Ophthalmic Res 1976;8:262–275
          DOI: 10.1159/000264832
          SO-VID: c6ac8868-1885-480f-8de9-531f53f8d0c5
          Copyright © © 1976 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 06 February 1976
          Date accepted : 30 March 1976
          Page count
          Pages: 14
          Categories
          Subject: Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Alloxan damage,Corneal epithelium,Stromal oedema,Opacification,Vascularization
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Alloxan damage, Corneal epithelium, Stromal oedema, Opacification, Vascularization

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