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Quantitative Analysis Versus Visual Assessment of Neuromelanin MR Imaging for the Diagnosis of Parkinson's disease.
Sofia Reimão
1
,
2 ,
Patrícia Pita Lobo
3
,
2 ,
Dulce Neutel
3
,
2 ,
Leonor Correia Guedes
3
,
2 ,
Miguel Coelho
3
,
2 ,
Mario M Rosa
3
,
2 ,
Joana Ferreira
4 ,
Daisy Abreu
2 ,
Nilza Gonçalves
2 ,
Carlos Morgado
1 ,
Rita G Nunes
4 ,
Jorge Campos
1 ,
Joaquim J Ferreira
2
,
5
2015
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Abstract
Specific MR sequences have been able to identify the loss of neuromelanin in the substantia nigra (SN) of early stage Parkinson's disease (PD) patients. Since this technique may have a significant impact in clinical patient management, easy and widely available imaging analysis is needed for routine use.