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      Transcript Levels of Androgen Receptor Variant 7 and Ubiquitin-Conjugating Enzyme 2C in Hormone Sensitive Prostate Cancer and Castration-Resistant Prostate Cancer.

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          Abstract

          This study is designed to identify the androgen receptor variant 7 (AR-V7) status, clinical significance of AR-V7 in hormone sensitive prostate cancer (HSPC). Then, we evaluated AR-V7 and changes of its target gene, ubiquitin-conjugating enzyme E2C (UBE2C) which is an anaphase-promoting complex/cyclosome (APC/C)-specific ubiquitin-conjugating enzyme, in castration-resistant prostate cancer (CRPC) in serial tumor biopsies from patients receiving androgen deprivation therapy.

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          Author and article information

          Journal
          Prostate
          The Prostate
          Wiley
          1097-0045
          0270-4137
          January 2017
          : 77
          : 1
          Affiliations
          [1 ] Department of Urology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea.
          [2 ] Department of Pharmacology, Pusan National University School of Medicine, Yangsan, Republic of Korea.
          [3 ] Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
          [4 ] Biomedical Research Institute, Pusan National University School of Medicine, Busan, Republic of Korea.
          Article
          10.1002/pros.23248
          27550197

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