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Silver-stained nucleolar organizer regions in the uterine myomatous tumors
October 1996
October 1996
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Abstract
The numbers of silver-stained nucleolar organizer regions (AgNORs) were counted in
uterine myomatous tumors, and compared with those in corresponding normal myometria.
The mean number of AgNORs in myomatous tumors tended to increase according to the
neoplastic changes. The mean number of AgNORs in leiomyosarcoma (6.4 +/- 0.9) was
significantly higher than that in cellular leiomyoma (4.5 +/- 0.7, P < 0.01). or leiomyoma
(3.0 +/- 0.5, P < 0.001). In the normal myometria, the mean number of AgNORs (3.3
+/- 0.4) in the premenopausal women showed a higher tendency than that in the post-menopausal
women (2.4 +/- 0.5). These results therefore suggest that AgNOR counts may be useful
for diagnosis of cellular activity in uterine myomatous tumors.