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      Guidance on the use of the weight of evidence approach in scientific assessments

      research-article
      EFSA Scientific Committee, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,
      EFSA Journal
      John Wiley and Sons Inc.
      risk assessment, weight of evidence, biological relevance, uncertainty, lines of evidence

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          Abstract

          EFSA requested the Scientific Committee to develop a guidance document on the use of the weight of evidence approach in scientific assessments for use in all areas under EFSA's remit. The guidance document addresses the use of weight of evidence approaches in scientific assessments using both qualitative and quantitative approaches. Several case studies covering the various areas under EFSA's remit are annexed to the guidance document to illustrate the applicability of the proposed approach. Weight of evidence assessment is defined in this guidance as a process in which evidence is integrated to determine the relative support for possible answers to a question. This document considers the weight of evidence assessment as comprising three basic steps: (1) assembling the evidence into lines of evidence of similar type, (2) weighing the evidence, (3) integrating the evidence. The present document identifies reliability, relevance and consistency as three basic considerations for weighing evidence.

          Abstract

          This publication is linked to the following EFSA Supporting Publications article: http://onlinelibrary.wiley.com/doi/10.2903/sp.efsa.2017.EN-1295/full

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          Most cited references47

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          Guidance of the Scientific Committee on Transparency in the Scientific Aspects of Risk Assessments carried out by EFSA. Part 2: General Principles

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              A methodology for systematic mapping in environmental sciences

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                Author and article information

                Journal
                EFSA J
                EFSA J
                10.1002/(ISSN)1831-4732
                EFS2
                EFSA Journal
                John Wiley and Sons Inc. (Hoboken )
                1831-4732
                03 August 2017
                August 2017
                : 15
                : 8 ( doiID: 10.1002/efs2.2017.15.issue-8 )
                : e04971
                Author notes
                Article
                EFS24971
                10.2903/j.efsa.2017.4971
                7009893
                32625632
                c78be1e6-b1af-457d-8362-b6ac7c22006a
                © 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.

                History
                Page count
                Figures: 7, Tables: 17, Pages: 69, Words: 37508
                Categories
                Scientific Opinion
                Scientific Opinion
                Custom metadata
                2.0
                August 2017
                Converter:WILEY_ML3GV2_TO_JATSPMC version:5.7.5 mode:remove_FC converted:21.01.2020

                risk assessment,weight of evidence,biological relevance,uncertainty,lines of evidence

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