Age-related macular degeneration (AMD) is the primary cause of the blindness of the elderly. Among the population aged more than 50 years old, the prevalence of AMD increases with age growing. With the advent of aging society, the number of people with AMD is increasing year by year. Although in recent years the researchers have done a lot of basic and clinical research on the pathogenesis and treatment method of AMD, its pathogenesis remains controversial and there are no ideal treatment methods. This paper made a review about the pathogenesis and treatment methods of AMD in recent years and pointed out that the occurrence and development of AMD are very complex and many regulatory factors and cells are involved. However, more research should be conducted to confirm the pathogenesis and treatment methods.