1
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Surgeon-led 7-VINCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery Service

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Antibiotic stewardship programs optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. In this prospective interventional study, a multidisciplinary team led by surgeons implemented a program aimed at shortening the duration of antibiotic treatment <7 days. The impact of the intervention on antibiotic consumption adjusted to bed-days and discharges, and the isolation of multiresistant bacteria (MRB) was also studied. Furthermore, the surgeons were surveyed regarding their beliefs and feelings about the program. Out of 1409 patients, 40.7% received antibiotic therapy. Treatment continued for over 7 days in 21.5% of cases, and, as can be expected, source control was achieved in only 48.8% of these cases. The recommendations were followed in 90.2% of cases, the most frequent being to withdraw the treatment (55.6%). During the first 16 months of the intervention, a sharp decrease in the percentage of extended treatments, with R 2 = 0.111 was observed. The program was very well accepted by surgeons, and achieved a decrease in both the consumption of carbapenems and in the number of MRB isolations. Multidisciplinary stewardship teams led by surgeons seem to be well received and able to better manage antibiotic prescription in surgery.

          Related collections

          Most cited references56

          • Record: found
          • Abstract: found
          • Article: not found

          Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.

          Many different definitions for multidrug-resistant (MDR), extensively drug-resistant (XDR) and pandrug-resistant (PDR) bacteria are being used in the medical literature to characterize the different patterns of resistance found in healthcare-associated, antimicrobial-resistant bacteria. A group of international experts came together through a joint initiative by the European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC), to create a standardized international terminology with which to describe acquired resistance profiles in Staphylococcus aureus, Enterococcus spp., Enterobacteriaceae (other than Salmonella and Shigella), Pseudomonas aeruginosa and Acinetobacter spp., all bacteria often responsible for healthcare-associated infections and prone to multidrug resistance. Epidemiologically significant antimicrobial categories were constructed for each bacterium. Lists of antimicrobial categories proposed for antimicrobial susceptibility testing were created using documents and breakpoints from the Clinical Laboratory Standards Institute (CLSI), the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and the United States Food and Drug Administration (FDA). MDR was defined as acquired non-susceptibility to at least one agent in three or more antimicrobial categories, XDR was defined as non-susceptibility to at least one agent in all but two or fewer antimicrobial categories (i.e. bacterial isolates remain susceptible to only one or two categories) and PDR was defined as non-susceptibility to all agents in all antimicrobial categories. To ensure correct application of these definitions, bacterial isolates should be tested against all or nearly all of the antimicrobial agents within the antimicrobial categories and selective reporting and suppression of results should be avoided. © 2011 European Society of Clinical Microbiology and Infectious Diseases. No claim to original US government works.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

            To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012".
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship.

                Bookmark

                Author and article information

                Journal
                Antibiotics (Basel)
                Antibiotics (Basel)
                antibiotics
                Antibiotics
                MDPI
                2079-6382
                24 December 2020
                January 2021
                : 10
                : 1
                : 11
                Affiliations
                [1 ]Department of Surgery, Hospital General Granollers, Universitat Internacional de Catalunya, 08402 Granollers, Spain; mbatlle@ 123456fphag.org (M.B.); mjuvany@ 123456fphag.org (M.J.); pruizdeleon@ 123456fphag.org (P.R.-d.L.)
                [2 ]Department of Clinical Pharmacy, Hospital General Granollers, 08402 Granollers, Spain; msagales@ 123456fphag.org
                [3 ]Department of Clinical Microbiology, Hospital General Granollers, 08402 Granollers, Spain; apulido@ 123456fphag.org
                [4 ]Department of Statistics and Research, Hospital General Granollers, 08402 Granollers, Spain; gmolist@ 123456fphag.org
                [5 ]Infectious Diseases Unit, Hospital General Granollers, 08402 Granollers, Spain; jcuquet@ 123456fphag.org
                Author notes
                [* ]Correspondence: jmbadia@ 123456fphag.org or jmbadiaperez@ 123456gmail.com ; Tel.: +34-670702099
                Author information
                https://orcid.org/0000-0003-2928-5233
                https://orcid.org/0000-0002-0927-1945
                Article
                antibiotics-10-00011
                10.3390/antibiotics10010011
                7823351
                33374393
                c7ae1b84-c3ac-4d4e-ac5f-6078feb89500
                © 2020 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 17 November 2020
                : 23 December 2020
                Categories
                Article

                anti-bacterial agents/therapeutic use*,antimicrobial stewardship/organization and administration*,antimicrobial stewardship/statistics and numerical data*,drug resistance,multiple,bacterial/drug effects,infection control/organization and administration,general surgery/standards*,surgical wound infection/prevention and control

                Comments

                Comment on this article