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      Premna integrifolia L.: A review of its biodiversity, traditional uses and phytochemistry

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          Abstract

          Premna integrifolia Linn. (Verbenaceae) is an important woody, medicinal plant and has been prominent place in Ayurveda, Siddha and Unani system of medicines. Objective of the present review is to avail the comprehensive information on ecological biodiversity, traditional uses and phytochemistry of P. integrifolia. Information of the plant was searched using various electronic databases in reference to the terms Premna integrifolia, ecological biodiversity, traditional uses and phytoconstituents of P. integrifolia along with Ayurvedic books, Indian classical texts, pharmacopoeias, journals, etc. There is an inherent difference within the three Ayurvedic Formulary of India (AFIs) published with regard to the botanical sources of Agnimanthā. Complete data of the plant has been collected manually since from the years 1947–2015 and was arranged accordingly. Available data have reports that roots of P. integrifolia are widely used for the preparation of Ayurvedic formulations like Daśamūlakvātha, Ariṣṭa, Cūrṇa and Chayawanprashavleh for the treatment of a variety of afflictions. It has also reported to have p-methoxy cinnamic acid, linalool, linoleic acid, β-sitosterol and flavone luteolin, iridoid glycoside, premnine, ganiarine and ganikarine, premnazole, aphelandrine, pentacyclic terpene betulin, caryophellen, premnenol, premna spirodiene, clerodendrin-A, etc., phytoconstituents in its various parts. There is need to validate its traditional uses, isolation and confirmation of reported phytoconstituents, biological and clinical efficacy by modern analytical and biological techniques which could be recommendation for further scientific research.

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                Author and article information

                Journal
                Anc Sci Life
                Anc Sci Life
                ASL
                Ancient Science of Life
                Medknow Publications & Media Pvt Ltd (India )
                0257-7941
                2249-9547
                Jul-Sep 2015
                : 35
                : 1
                : 4-11
                Affiliations
                Department of Pharmacology, NGSPMS, College of Pharmacy, Brahma Valley Educational Campus, Nashik, Maharashtra, India
                Author notes
                Address for correspondence: Prof. Prashant Y. Mali, Department of Pharmacology, NGSPMS, College of Pharmacy, Anjaneri, Trimbak Road, Nashik - 422 213, Maharashtra, India. E-mail: pymali2008@ 123456rediffmail.com
                Article
                ASL-35-4
                10.4103/0257-7941.165624
                4623632
                Copyright: © Ancient Science of Life

                This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

                Categories
                Review Article

                Life sciences

                traditional uses, premna integrifolia, phytochemistry, ecological biodiversity

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