+1 Recommend
1 collections
      • Record: found
      • Abstract: found
      • Article: found

      The Thymic Hormones

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          The existence of a specific hormone of the thymus could be demonstrated with the traditional tests: The observation of the consequences of thymectomy. The possibility to suppress these consequences by a specific therapy. This succeeded by means of thymic grafts and by means of injections of an adequate thymus extract. (Several extracts of demonstrated substitutive potency have been prepared.) A presumably pure chemical entity was isolated, which suppresses the consequences of thymectomy as completely as the total extract. There is circumstantial evidence for the assumption, that under normal conditions this substance is secreted into the circulation. Lymphocytes act presumably as its vectors. The most conspicuous features of the physiological role of the thymic are: (1) Its influence upon the lymphocytes. (2) Its interactions with other hormones. (3) Its role in the development of the immunitary reactions. The complete study of the functions of the thymus under all these aspects has been performed thus far only with the presumably pure substance mentioned above. The question, whether the thymus secretes one or several hormones, can not be answered thus far. (A mention is made of the substances obtained from the thymus and active on the growth of malignant tumours.)

          Related collections

          Author and article information

          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          21 November 2008
          : 2
          : 4
          : 226-255
          178237 Hormones 1971;2:226–255
          © 1971 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 30


          Comment on this article