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      An estimated glomerular filtration rate equation for the full age spectrum.

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          Abstract

          Glomerular filtration rate (GFR) is accepted as the best indicator of kidney function and is commonly estimated from serum creatinine (SCr)-based equations. Separate equations have been developed for children (Schwartz equation), younger and middle-age adults [Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation] and older adults [Berlin Initiative Study 1 (BIS1) equation], and these equations lack continuity with ageing. We developed and validated an equation for estimating the glomerular filtration rate that can be used across the full age spectrum (FAS).

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          Author and article information

          Journal
          Nephrol. Dial. Transplant.
          Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
          Oxford University Press (OUP)
          1460-2385
          0931-0509
          May 2016
          : 31
          : 5
          Affiliations
          [1 ] Department of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.
          [2 ] Exploration Fonctionnelle Rénale, Groupement Hospitalier Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
          [3 ] Charité University Hospital, Institute of Public Health, Berlin, Germany.
          [4 ] Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsø, Norway.
          [5 ] Clinical Biochemistry, East Kent Hospitals University NHS Foundation Trust, Canterbury, Kent, UK.
          [6 ] Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
          [7 ] Emeritus Professor of Medicine, Geffen School of Medicine at UCLA, Laguna Niguel, CA, USA.
          [8 ] Universidade Federal do Rio Grande do Sul, FAMED - Programa de Pós Graduação em Saúde da Criança e do Adolescente, Porto Alegre, Brazil.
          [9 ] Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
          [10 ] Service de Néphrologie, Dialyse et Transplantation Rénale, Hôpital Nord, CHU de Saint-Etienne, Saint-Etienne, France.
          [11 ] Department of Clinical Chemistry, AZ Groeninge Hospital, Kortrijk, Belgium.
          [12 ] Nephrology-Dialysis-Transplantation, University of Liège, CHU Sart Tilman, Liège, Belgium.
          Article
          gfv454
          10.1093/ndt/gfv454
          4848755
          26932693

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