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      Edaravone promotes activation of resident cardiac stem cells by transplanted mesenchymal stem cells in a rat myocardial infarction model.

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          Abstract

          To explore the effect of edaravone on bone marrow mesenchymal stem cells (BMSCs) transplanted to treat acute myocardial infarction (AMI) and the underlying mechanism.

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          Author and article information

          Journal
          J. Thorac. Cardiovasc. Surg.
          The Journal of thoracic and cardiovascular surgery
          Elsevier BV
          1097-685X
          0022-5223
          Aug 2016
          : 152
          : 2
          Affiliations
          [1 ] Department of Cardiac Surgery, The First Hospital of China Medical University, Shenyang, China.
          [2 ] Department of Cardiac Surgery, The First Hospital of China Medical University, Shenyang, China. Electronic address: cmugtx@sina.com.
          [3 ] Department of Anesthesiology, The First Hospital of China Medical University, Shenyang, China; Department of Anesthesiology of the First Affiliated Hospital of Dalian Medical University, Dalian, China.
          [4 ] Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Cardiovascular Institute, Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu, China.
          [5 ] Department of Radiology, The First Hospital of China Medical University, Shenyang, China; Key Laboratory of Diagnostic Imaging and Interventional Radiology of Liaoning Province, The First Hospital of China Medical University, Shenyang, China.
          [6 ] Department of Echocardiography, The First Hospital of China Medical University, Shenyang, China.
          [7 ] Institute of Genetic Medicine, School of Life Science, State Key Laboratory of Biotherapy, Sichuan University, Chengdu, China.
          Article
          S0022-5223(16)00430-X
          10.1016/j.jtcvs.2016.02.071
          27056755
          c899094f-834f-4d51-af2d-238730d4f22e
          History

          edaravone,stem cell transplantation,ventricular function,regeneration,myocardial infarction

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