Update on the Mapping of Prevalence and Intensity of Infection for Soil-Transmitted Helminth Infections in Latin America and the Caribbean: A Call for Action

Abstract

It is estimated that in Latin America and the Caribbean (LAC) at least 13.9 million preschool age and 35.4 million school age children are at risk of infections by soil-transmitted helminths (STH): Ascaris lumbricoides, Trichuris trichiura and hookworms ( Necator americanus and Ancylostoma duodenale). Although infections caused by this group of parasites are associated with chronic deleterious effects on nutrition and growth, iron and vitamin A status and cognitive development in children, few countries in the LAC Region have implemented nationwide surveys on prevalence and intensity of infection. The aim of this study was to identify gaps on the mapping of prevalence and intensity of STH infections based on data published between 2000 and 2010 in LAC, and to call for including mapping as part of action plans against these infections. A total of 335 published data points for STH prevalence were found for 18 countries (11.9% data points for preschool age children, 56.7% for school age children and 31.3% for children from 1 to 14 years of age). We found that 62.7% of data points showed prevalence levels above 20%. Data on the intensity of infection were found for seven countries. The analysis also highlights that there is still an important lack of data on prevalence and intensity of infection to determine the burden of disease based on epidemiological surveys, particularly among preschool age children. This situation is a challenge for LAC given that adequate planning of interventions such as deworming requires information on prevalence to determine the frequency of needed anthelmintic drug administration and to conduct monitoring and evaluation of progress in drug coverage.

Author Summary

Soil-transmitted helminths (STH) are part of the group of neglected infectious diseases (NID) in Latin America and the Caribbean (LAC), and are associated with several adverse chronic effects on child health. Although control interventions such as periodic administration of anthelmintic drugs, health education, improved access to safe water and sanitation, among others, are acknowledged to be an important means to reduce morbidity and to achieve control, epidemiological information on prevalence status is lacking at the lowest sub-national administrative levels (municipalities, districts or provinces) in many countries thus hindering decision making regarding not only the treatment, but also the monitoring of progress in deworming coverage, the assessment of epidemiological impact on parasite prevalence and load and, therefore, the achievement of the overall public health goals. Epidemiological surveys can be expensive and require time and effort for their implementation, which could explain the low number of studies published with data on prevalence and intensity of infection in the Americas. The use of alternative methodologies, for instance those based on geographical information systems and remote sensing technologies, or of sentinel surveillance in schools may help countries in the task of collecting information and support the implementation of integrated control programs against STH.