The immunocytochemical localization of somatostatin-containing neurons in the rat central nervous system

Roger, L.J.; Petrusz, P; Maderdrut, J.L.; Finley, J.C.W.

doi:10.1016/0306-4522(81)90006-3

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The immunocytochemical localization of somatostatin-containing neurons in the rat central nervous system

Author(s): J.C.W. Finley , J.L. Maderdrut , L.J. Roger , P. Petrusz

Publication date Created: November 1981

Publication date (Print): November 1981

Journal: Neuroscience

Publisher: Elsevier BV

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Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone.

P Brazeau, W. Vale, R Burgus … (1973)

A peptide has been isolated from ovine hypothalamus which, at 1 x 10(-9)M, inhibits secretion in vitro of immunoreactive rat or human growth hormones and is similarly active in vivo in rats. Its structure is H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH The synthetic replicate is biologically active.