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Abstract
Neuroimaging is now entering a more mature era, whereby we can ask sophisticated questions
concerning the biologic behavior of brain tumors. Multimodality imaging (CT, MRI,
PET) offers the most precise information noninvasively on tumor type and grade, guides
therapeutic choices, and assesses the effects of therapy. The incorporation of functional
MRI (such as diffusion-weighted imaging, diffusion tensor imaging, proton MR spectroscopy,
and perfusion-weighted imaging) has allowed neuro-oncologists a window of opportunity
to assess the biologic behavior of brain neoplasms. These new multimodality approaches
will be routinely used preoperatively, intraoperatively, and eventually, therapeutically.