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      Aplicación del Valor Umbral del Número de Ciclos (Ct) de PCR en la COVID-19 Translated title: Application of the PCR Number of Cycle Threshold Value (Ct) in COVID-19

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          Abstract

          La pandemia por el SARS-CoV-2 persiste con toda su virulencia a pesar de haberse administrado 650.382.819 dosis de vacuna anti-COVID a nivel mundial. La prueba de referencia para la identificación de la infección es la reacción en cadena de la polimerasa con transcriptasa inversa (RT-qPCR). La utilidad de esta prueba puede disminuir al simplificar su resultado como positivo o negativo. Determinar el número de ciclos (Ct) en las pruebas RT-qPCR positivas puede ayudar en la toma de decisiones cuando se interpretan en el contexto clínico de los pacientes.

          Translated abstract

          The SARS-CoV-2 pandemic persists with all its virulence despite 650,382,819 doses of COVID vaccine worldwide. The reference test for infection identification is reverse transcription polymerase chain reaction (RT-qPCR). The usefulness of this test may be diminished by simplifying its result as positive or negative. Determining the number of cycles (Ct) in positive RT-qPCR tests can assist in decision-making when interpreted in the clinical context of patients.

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          Author and article information

          Journal
          Semergen
          Semergen
          Semergen
          Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Published by Elsevier España, S.L.U.
          1138-3593
          1578-8865
          27 May 2021
          27 May 2021
          Affiliations
          [1 ]licenciado en medicina, Especialista en Medicina Familiar y Comunitaria. Centro de Salud Universitario de Pinto (Madrid), Servicio Madrileño de Salud Search for articles by this author in MEDLINE®, Spain
          [2 ]Doctor en Medicina, Especialista en Medicina Interna y en Medicina Preventiva y Salud Pública. Colaborador honorífico de la Universidad de Castilla-La Mancha, Universidad de Castilla-La Mancha Search for articles by this author in MEDLINE®, Spain
          [3 ]Doctor en Medicina. Licenciado en Farmacia, Resp. Serv. de Farmacia Gerencia AP Gran Canaria (SFAP) Vicepresidente Comité Ético Investigación con medicamento Hospital Dr. Negrín Gran Canaria Las Palmas (CEI/CEIm), Servicio Canario de Salud Search for articles by this author in MEDLINE®, Spain
          [4 ]Doctor en Medicina, Especialista en Medicina Familiar y Comunitaria. Consultorio local Fontanars dels Alforins (Valencia), Agència Valenciana de Salut Search for articles by this author in MEDLINE®, Spain
          [5 ]licenciado en medicina, Especialista en Medicina Familiar y Comunitaria. EAP de Trujillo /Cáceres), Servicio Extremeno de Salud Search for articles by this author in MEDLINE®
          [6 ]licenciado en medicina, Especialista en Medicina Familiar y Comunitaria. Centro de Salud de la Alamedilla (Salamanca), Servicio de Salud Castilla y León, Spain
          [7 ]Licenciado en medicina, Getxo, Bizkaia, España
          Author notes
          [* ]Autor correspondencia
          Article
          S1138-3593(21)00137-4
          10.1016/j.semerg.2021.05.003
          8156904
          © 2021 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Published by Elsevier España, S.L.U. All rights reserved.

          Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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