Insulinemia and Blood Pressure Responses to Oral Glucose Load in Primary Hypertensive Patients

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Fourteen hypertensive patients and 14 normotensive control subjects were submitted to the oral glucose test and their plasma potassium, glucose and insulin levels were measured. Cardiovascular responses were evaluated by blood pressure and pulse rate measurements. Five of 14 hypertensive patients were hyperinsulinemic and had higher blood glucose levels, suggesting insulin resistance. Systolic blood pressure, heart rate and double product increased significantly in normotensive subjects and slightly in hyperinsulinemic patients, but not in normoinsulinemic hypertensive patients. These results seem to indicate the presence of insulin resistance in a particular group of primary hypertensive patients and a smaller cardiovascular response after glucose overload.

Related collections

Author and article information

Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 1991

Publication date (Print): 1991

Publication date (Electronic): 12 November 2008

Volume: 79

Issue: 1

Pages: 14-19

Affiliations

Department of Internal Medicine, School of Medicine, Campinas State University, São Paulo, Brazil

Article

Publisher ID: 174852 Other ID: Cardiology 1991;79:14–19

DOI: 10.1159/000174852

PubMed ID: 1777910

SO-VID: c9ccd484-0b63-46c1-9a10-1af060936107

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date received : 26 November 1990

Date accepted : 21 January 1991

Page count

Pages: 6

Comments

Comment on this article

Cited by 2

See all cited by

- Version 1

Call for Papers: Novel Methods in Vascular and Lymphatic Physiology

Submit here by June 30, 2025