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      Effect of dietary fat and cholesterol on plasma lipids and lipoprotein fractions in normolipidemic men.

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          Abstract

          In a controlled feeding situation, male subjects were assigned to one of four treatment groups: low fat (31% of total kcal)/low cholesterol (193 mg/d) (LFLC), low fat/usual cholesterol (504 mg/d) (LFUC), usual fat (46% of total kcal)/low cholesterol (UFLC) and usual fat/usual cholesterol (UFUC) intake. For the first 2 wk of the 10-wk study all subjects consumed the UFUC diet. Subjects consumed experimental diets during wk 3-7 and resumed their customary intake during wk 8-10. Plasma total, high-density-lipoprotein (HDL), low-density-lipoprotein and very-low-density-lipoprotein cholesterol and triglycerides were determined weekly. A significant effect (P less than 0.05) of dietary fat on plasma total and HDL cholesterol was observed between the end of wk 2 and 7. Low fat intake resulted in 17 +/- 2 mg/dL lower total cholesterol and 10 +/- 1 mg/dL lower HDL cholesterol than the usual fat intake. Plasma lipids were not affected either by dietary cholesterol or by any interaction of dietary fat with cholesterol.

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          Author and article information

          Journal
          J. Nutr.
          The Journal of nutrition
          Oxford University Press (OUP)
          0022-3166
          0022-3166
          May 1988
          : 118
          : 5
          Affiliations
          [1 ] Department of Human Nutrition and Foods, Virginia Polytechnic Institute and State University, Blacksburg 24061.
          Article
          10.1093/jn/118.5.555
          3163364
          c9f48ec0-d81d-455d-a717-ecd24954939d
          History

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