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      Sepsis and septic shock.

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          Abstract

          Early recognition of sepsis and septic shock in children relies on obtaining an attentive clinical history, accurate vital signs, and a physical examination focused on mental status, work of breathing, and circulatory status. Laboratory tests may support the diagnosis but are not reliable in isolation. The goal of septic shock management is reversal of tissue hypoperfusion. The therapeutic end point is shock reversal. Mortality is significantly better among children when managed appropriately. Every physician who cares for children must strive to have a high level of suspicion and keen clinical acumen for recognizing the rare but potentially seriously ill child.

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          Author and article information

          Journal
          Emerg. Med. Clin. North Am.
          Emergency medicine clinics of North America
          1558-0539
          0733-8627
          Aug 2013
          : 31
          : 3
          Affiliations
          [1 ] Department of Emergency Medicine, University of Colorado School of Medicine, Denver Health Medical Center, 660 Bannock Street, MC 0108, Denver, CO 80204, USA. patrick.maloney@dhha.org
          Article
          S0733-8627(13)00043-6
          10.1016/j.emc.2013.04.006
          23915595
          ca04ddac-369c-4d8f-92bd-4a29ec08f05c
          Copyright © 2013 Elsevier Inc. All rights reserved.
          History

          Children,Early goal-directed therapy,Sepsis,Septic shock,Systemic inflammatory response syndrome (SIRS),Vasopressors

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