Blog
About

6
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Quantitative profiling and identification of plasma proteins of spinocerebellar ataxia type 2 patients.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Spinocerebellar ataxia type 2 (SCA2) is an autosomal-dominant hereditary ataxia characterized by progressive gait and limb ataxia, dysarthria, slow saccades, neuropathy and dementia. The expansion of trinucleotide CAG repeats in the coding region of the ATXN-2 gene leads to expanded polyglutamine stretch in the mutated protein which causes neuronal death.

          Related collections

          Author and article information

          Journal
          Neurodegener Dis
          Neuro-degenerative diseases
          S. Karger AG
          1660-2862
          1660-2854
          2013
          : 12
          : 4
          Affiliations
          [1 ] Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
          Article
          000346585
          10.1159/000346585
          23735416

          Comments

          Comment on this article