Traumatic brain injury, paraquat exposure, and their relationship to Parkinson disease.

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Abstract

Traumatic brain injury (TBI) increased risk of Parkinson disease (PD) in many but not all epidemiologic studies, giving rise to speculations about modifying factors. A recent animal study suggested that the combination of TBI with subthreshold paraquat exposure increases dopaminergic neurodegeneration. The objective of our study was to investigate PD risk due to both TBI and paraquat exposure in humans.

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Journal

Journal ID (iso-abbrev): Neurology

Title: Neurology

ISSN (Electronic): 1526-632X

ISSN (Print): 0028-3878

Publication date (Electronic): Nov 13 2012

Volume: 79

Issue: 20

Affiliations

[1 ] Department of Epidemiology, Fielding School of Public Health, University of California at Los Angeles, Los Angeles, CA, USA. pel27@ucla.edu

Article

Publisher Item ID: 79/20/2061

DOI: 10.1212/WNL.0b013e3182749f28

PubMed ID: 23150532

SO-VID: cadc1867-f934-4717-bbff-d3ca15754803

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