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      Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors.

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          Abstract

          We examined longitudinally the course and predictors of treatment resistance in a large cohort of first-episode psychosis (FEP) patients from initiation of antipsychotic treatment. We hypothesized that antipsychotic treatment resistance is: (a) present at illness onset; and (b) differentially associated with clinical and demographic factors.

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          Author and article information

          Journal
          Psychol Med
          Psychological medicine
          Cambridge University Press (CUP)
          1469-8978
          0033-2917
          Aug 2017
          : 47
          : 11
          Affiliations
          [1 ] Institute of Psychiatry, Psychology and Neuroscience, King's College London,London,UK.
          [2 ] School of Psychiatry, University of New South Wales, Sydney, NSW,Australia.
          [3 ] Department of Biostatistics,Institute of Psychiatry, Psychology and Neuroscience, King's College London,London,UK.
          [4 ] Health Service and Population Research Department,Institute of Psychiatry, Psychology and Neuroscience, King's College London,London,UK.
          [5 ] Addictions Department,Institute of Psychiatry, Psychology and Neuroscience, King's College London,London,UK.
          [6 ] Department of Psychiatry,Trinity College,Dublin, Republic ofIreland.
          [7 ] Department of Psychiatry,University of Cambridge,Cambridge,UK.
          [8 ] Division of Psychiatry,University of Nottingham,Nottingham,UK.
          Article
          S0033291717000435
          10.1017/S0033291717000435
          28395674
          cb1db5cd-9552-411b-959a-98417b9b4575
          History

          Clozapine,First-Episode- Psychosis,Schizophrenia,Treatment-Resistant,Treatment-Response

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